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    Pet100 PET100 cytochrome c oxidase chaperone [ Rattus norvegicus (Norway rat) ]

    Gene ID: 688786, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Pet100provided by RGD
    Official Full Name
    PET100 cytochrome c oxidase chaperoneprovided by RGD
    Primary source
    RGD:1585222
    See related
    Ensembl:ENSRNOG00000050169 AllianceGenome:RGD:1585222
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable unfolded protein binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be integral component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human PET100 (PET100 cytochrome c oxidase chaperone). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 149.4), Kidney (RPKM 115.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Pet100 in Genome Data Viewer
    Location:
    12p12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (6477703..6480435)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (1679805..1682540)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (2170630..2173259)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene calmodulin regulated spectrin-associated protein family, member 3 Neighboring gene XPA binding protein 2 Neighboring gene uncharacterized LOC103690858 Neighboring gene Purkinje cell protein 2 Neighboring gene syntaxin binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein PET100 homolog, mitochondrial
    Names
    PET100 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195245.1 → NP_001182174.1  protein PET100 homolog, mitochondrial

      See identical proteins and their annotated locations for NP_001182174.1

      Status: VALIDATED

      Source sequence(s)
      AA858572, CK840544, DY560095
      UniProtKB/TrEMBL
      A6KQ16, A6KQ18
      Conserved Domains (1) summary
      pfam09803
      Location:2 → 62
      Pet100

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      6477703..6480435
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039089765.2 → XP_038945693.1  protein PET100 homolog, mitochondrial isoform X1

      Related
      ENSRNOP00000067747.2
      Conserved Domains (1) summary
      pfam09803
      Location:24 → 73
      Pet100
    Nucleotide Protein Strain
    Heading Accession and Version

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