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    Cd200r1l CD200 receptor 1-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501779, updated on 29-Feb-2024

    Summary

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    Official Symbol
    Cd200r1lprovided by RGD
    Official Full Name
    CD200 receptor 1-likeprovided by RGD
    Primary source
    RGD:1563387
    See related
    Ensembl:ENSRNOG00000002046 AllianceGenome:RGD:1563387
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cd200r2; RGD1563387
    Summary
    Predicted to enable signaling receptor activity. Predicted to be involved in regulation of neuroinflammatory response. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CD200R1L (CD200 receptor 1 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 66.1), Liver (RPKM 36.0) and 3 other tissues See more
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    Genomic context

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    See Cd200r1l in Genome Data Viewer
    Location:
    11q21
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (69348638..69366916, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (55842632..55860914, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (60803856..60828979, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551884 Neighboring gene thymosin beta-10-like Neighboring gene synaptotagmin binding, cytoplasmic RNA interacting protein, pseudogene 1 Neighboring gene CD200 receptor 1 Neighboring gene ribosomal oxygenase 2, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Structural and functional heterogeneity in the CD200R family of immunoregulatory molecules and their expression at the feto-maternal interface. Gorczynski RM, et al. Am J Reprod Immunol, 2004 Aug. PMID 15274657
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of neuroinflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    cell surface glycoprotein CD200 receptor 1-like
    Names
    Cd200 receptor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      69348638..69366916 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008768757.4 → XP_008766979.1  cell surface glycoprotein CD200 receptor 1-like

      See identical proteins and their annotated locations for XP_008766979.1

      UniProtKB/TrEMBL
      D3ZJX0, D3ZPY4
      Conserved Domains (2) summary
      cd00096
      Location:41 → 46
      Ig; Ig strand A [structural motif]
      cl11960
      Location:41 → 147
      Ig; Immunoglobulin domain

    2. XM_008768755.4 → XP_008766977.1  cell surface glycoprotein CD200 receptor 1-like

      See identical proteins and their annotated locations for XP_008766977.1

      UniProtKB/TrEMBL
      D3ZJX0, D3ZPY4
      Conserved Domains (2) summary
      cd00096
      Location:41 → 46
      Ig; Ig strand A [structural motif]
      cl11960
      Location:41 → 147
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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