Ly6e lymphocyte antigen 6 family member E [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ly6eprovided by RGD
Official Full Name: lymphocyte antigen 6 family member Eprovided by RGD
Primary source: RGD:1565342
See related: Ensembl:ENSRNOG00000007091 AllianceGenome:RGD:1565342
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Predicted to be involved in negative regulation of viral entry into host cell. Predicted to act upstream of or within several processes, including epinephrine secretion; norepinephrine metabolic process; and ventricular cardiac muscle tissue morphogenesis. Predicted to be located in synapse. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Predicted to be anchored component of membrane. Orthologous to human LY6E (lymphocyte antigen 6 family member E). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Lung (RPKM 305.1), Adrenal (RPKM 246.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q34

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (108815970..108820444)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (106935530..106939689)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (116355426..116359862)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables acetylcholine receptor binding	ISO Inferred from Sequence Orthology more info
enables acetylcholine receptor inhibitor activity	IBA Inferred from Biological aspect of Ancestor more info
enables acetylcholine receptor inhibitor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within acetylcholine receptor signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within adrenal gland development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within epinephrine secretion	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within in utero embryonic development	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of viral entry into host cell	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within norepinephrine metabolic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within organ growth	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within ventricular cardiac muscle tissue morphogenesis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: lymphocyte antigen 6E

Names: lymphocyte antigen 6 complex, locus E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.