Lipt2 lipoyl(octanoyl) transferase 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lipt2provided by RGD
Official Full Name: lipoyl(octanoyl) transferase 2provided by RGD
Primary source: RGD:1305211
See related: Ensembl:ENSRNOG00000016906 AllianceGenome:RGD:1305211
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1305211
Summary: Predicted to enable lipoyl(octanoyl) transferase activity and octanoyl transferase activity (acting on glycine-cleavage complex H protein). Predicted to be involved in positive regulation of oxygen metabolic process and protein lipoylation. Predicted to be active in mitochondrion. Orthologous to human LIPT2 (lipoyl(octanoyl) transferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Adrenal (RPKM 31.3), Heart (RPKM 23.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q32

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (163916695..163919022)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (154504563..154506890)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (165170645..165172972)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables lipoyl(octanoyl) transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables lipoyl(octanoyl) transferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in positive regulation of oxygen metabolic process	ISO Inferred from Sequence Orthology more info
involved_in protein lipoylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial

Names: lipoyl(octanoyl) transferase 2 (putative); putative lipoyltransferase 2, mitochondrial

NP_001102387.1

EC 2.3.1.181

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.