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    Fam3c FAM3 metabolism regulating signaling molecule C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 312159, updated on 2-May-2024

    Summary

    Official Symbol
    Fam3cprovided by RGD
    Official Full Name
    FAM3 metabolism regulating signaling molecule Cprovided by RGD
    Primary source
    RGD:735193
    See related
    Ensembl:ENSRNOG00000060349 AllianceGenome:RGD:735193
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of gluconeogenesis. Predicted to be located in Golgi apparatus. Predicted to be active in extracellular space. Orthologous to human FAM3C (FAM3 metabolism regulating signaling molecule C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 267.4), Brain (RPKM 218.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Fam3c in Genome Data Viewer
    Location:
    4q22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (51805686..51853030, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (50839929..50887276, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (49388962..49439892, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene cadherin-like and PC-esterase domain containing 1 Neighboring gene Wnt family member 16 Neighboring gene ribosomal protein S2, pseudogene 30 Neighboring gene translationally-controlled tumor protein-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein FAM3C
    Names
    FAM3C-like protein
    family with sequence similarity 3, member C
    interleukin-like EMT inducer

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198771.2NP_942066.1  protein FAM3C precursor

      See identical proteins and their annotated locations for NP_942066.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/Swiss-Prot
      Q810F4
      UniProtKB/TrEMBL
      A0A0G2JUB0, A6IE64, A6IE65
      Related
      ENSRNOP00000069031.2, ENSRNOT00000077889.2
      Conserved Domains (1) summary
      cd13940
      Location:53223
      ILEI_FAM3C; Interleukin-like EMT inducer

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      51805686..51853030 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)