ALAS1 5'-aminolevulinate synthase 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: ALAS1provided by VGNC
Official Full Name: 5'-aminolevulinate synthase 1provided by VGNC
Primary source: VGNC:VGNC:69780
See related: Ensembl:ENSMMUG00000005596
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	2	NC_041755.1 (108336793..108353981)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	2	NC_027894.1 (90011731..90028936, complement)

Chromosome 2 - NC_041755.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH69932 (e-PCR)
- UniSTS:3329

RH93452 (e-PCR)
- UniSTS:90989

RH77906 (e-PCR)
- UniSTS:40822

D2S1587E (e-PCR)
- UniSTS:150671

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 5-aminolevulinate synthase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in erythrocyte development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in heme biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hemoglobin biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 5-aminolevulinate synthase, nonspecific, mitochondrial

Names: aminolevulinate, delta-, synthase 1

XP_001090440.3

EC 2.3.1.37

XP_014986247.2

EC 2.3.1.37

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041755.1 Reference Mmul_10 Primary Assembly

Range

108336793..108353981

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015130761.2 → XP_014986247.2 5-aminolevulinate synthase, nonspecific, mitochondrial

UniProtKB/TrEMBL

A0A5S6R787, A0A8J8XJZ5, F7H7H8, G7ML36, H9FR57

Conserved Domains (2) summary

pfam09029
Location:2 → 137

Preseq_ALAS; 5-aminolevulinate synthase presequence

cl18945
Location:197 → 602

Beta_elim_lyase; Beta-eliminating lyase
XM_001090440.4 → XP_001090440.3 5-aminolevulinate synthase, nonspecific, mitochondrial

UniProtKB/TrEMBL

A0A5S6R787, A0A8J8XJZ5, F7H7H8, G7ML36, H9FR57

Related

ENSMMUP00000007397.3, ENSMMUT00000007871.4

Conserved Domains (2) summary

pfam09029
Location:2 → 137

Preseq_ALAS; 5-aminolevulinate synthase presequence

cl18945
Location:197 → 602

Beta_elim_lyase; Beta-eliminating lyase