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    BC024139 cDNA sequence BC024139 [ Mus musculus (house mouse) ]

    Gene ID: 271278, updated on 8-Feb-2024

    Summary

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    Official Symbol
    BC024139provided by MGI
    Official Full Name
    cDNA sequence BC024139provided by MGI
    Primary source
    MGI:MGI:2442591
    See related
    Ensembl:ENSMUSG00000044361 AllianceGenome:MGI:2442591
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6230424I18Rik
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in several processes, including intermediate filament cytoskeleton organization; regulation of focal adhesion assembly; and wound healing. Predicted to be active in cytoplasm; cytoskeleton; and membrane. Predicted to colocalize with intermediate filament. Is expressed in corpus striatum and ventricular layer. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in CNS E11.5 (RPKM 10.2), CNS E14 (RPKM 7.5) and 10 other tissues See more
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    Genomic context

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    See BC024139 in Genome Data Viewer
    Location:
    15 D3; 15 35.4 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (76003717..76010756, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (76119517..76126556, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene nuclear receptor binding protein 2 Neighboring gene predicted gene, 41349 Neighboring gene epiplakin 1 Neighboring gene predicted gene, 52196 Neighboring gene predicted gene, 35087 Neighboring gene STARR-seq mESC enhancer starr_39044 Neighboring gene cyclin-dependent kinases regulatory subunit 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC37978

    General protein information

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    Preferred Names
    uncharacterized protein LOC271278

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001142968.1 → NP_001136440.1  uncharacterized protein LOC271278

      See identical proteins and their annotated locations for NP_001136440.1

      Status: VALIDATED

      Source sequence(s)
      AK078032, BC060242
      Consensus CDS
      CCDS49643.1
      UniProtKB/TrEMBL
      E9PXU3, Q8BVJ3
      Related
      ENSMUSP00000053305.6, ENSMUST00000054022.12
      Conserved Domains (2) summary
      cl02488
      Location:157 → 267
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cl02524
      Location:675 → 701
      GAS2; Growth-Arrest-Specific Protein 2 Domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      76003717..76010756 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_198172.2: Suppressed sequence

      Description
      NM_198172.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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