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    Zfp524 zinc finger protein 524 [ Mus musculus (house mouse) ]

    Gene ID: 66056, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Zfp524provided by MGI
    Official Full Name
    zinc finger protein 524provided by MGI
    Primary source
    MGI:MGI:1916740
    See related
    Ensembl:ENSMUSG00000051184 AllianceGenome:MGI:1916740
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf524; 0610012F07Rik; 2300009P13Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; and genitourinary system. Orthologous to human ZNF524 (zinc finger protein 524). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in colon adult (RPKM 16.2), duodenum adult (RPKM 15.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp524 in Genome Data Viewer
    Location:
    7 A1; 7 2.9 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (5018142..5021487)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (5015216..5018493)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53351 Neighboring gene Flt3 interacting zinc finger protein 1 Neighboring gene STARR-seq mESC enhancer starr_17950 Neighboring gene STARR-positive B cell enhancer ABC_E4889 Neighboring gene zinc finger protein 865 Neighboring gene STARR-positive B cell enhancer ABC_E3696 Neighboring gene zinc finger protein 784

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. An atlas of combinatorial transcriptional regulation in mouse and man. Ravasi T, et al. Cell, 2010 Mar 5. PMID 20211142, Free PMC Article
    2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 524

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418678.1 → NP_001405607.1  zinc finger protein 524

      Status: VALIDATED

      Source sequence(s)
      AC157563
      UniProtKB/Swiss-Prot
      Q9D0B1, Q9DCQ0
      Related
      ENSMUSP00000146921.2, ENSMUST00000207901.2

    2. NM_001418681.1 → NP_001405610.1  zinc finger protein 524

      Status: VALIDATED

      Source sequence(s)
      AC157563
      UniProtKB/Swiss-Prot
      Q9D0B1, Q9DCQ0
      Related
      ENSMUSP00000147095.2, ENSMUST00000209030.2

    3. NM_001418683.1 → NP_001405612.1  zinc finger protein 524

      Status: VALIDATED

      Source sequence(s)
      AC157563
      UniProtKB/Swiss-Prot
      Q9D0B1, Q9DCQ0

    4. NM_001418686.1 → NP_001405615.1  zinc finger protein 524

      Status: VALIDATED

      Source sequence(s)
      AC157563
      UniProtKB/Swiss-Prot
      Q9D0B1, Q9DCQ0

    5. NM_001418688.1 → NP_001405617.1  zinc finger protein 524

      Status: VALIDATED

      Source sequence(s)
      AC157563
      UniProtKB/Swiss-Prot
      Q9D0B1, Q9DCQ0

    6. NM_025324.3 → NP_079600.1  zinc finger protein 524

      See identical proteins and their annotated locations for NP_079600.1

      Status: VALIDATED

      Source sequence(s)
      AC157563
      Consensus CDS
      CCDS20752.1
      UniProtKB/Swiss-Prot
      Q9D0B1, Q9DCQ0
      Related
      ENSMUSP00000083533.4, ENSMUST00000086349.5
      Conserved Domains (2) summary
      COG5048
      Location:102 → 218
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:139 → 159
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RNA

    1. NR_184793.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC157563

    2. NR_184794.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC157563

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      5018142..5021487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D0B1.1 GenPept UniProtKB/Swiss-Prot:Q9D0B1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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