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    Cfap299 cilia and flagella associated protein 299 [ Mus musculus (house mouse) ]

    Gene ID: 75784, updated on 9-May-2024

    Summary

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    Official Symbol
    Cfap299provided by MGI
    Official Full Name
    cilia and flagella associated protein 299provided by MGI
    Primary source
    MGI:MGI:1916571
    See related
    Ensembl:ENSMUSG00000057816 AllianceGenome:MGI:1916571
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700007G11Rik; 4930428O21Rik
    Summary
    Located in cytoplasm. Is expressed in central nervous system; node; and reproductive system. Orthologous to human CFAP299 (cilia and flagella associated protein 299). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 12.5) See more
    Orthologs
    human all
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    Genomic context

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    See Cfap299 in Genome Data Viewer
    Location:
    5 E3; 5 47.77 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (98476998..98949912)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (98329138..98802053)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A730035I17 gene Neighboring gene PR domain containing 8 Neighboring gene fibroblast growth factor 5 Neighboring gene STARR-seq mESC enhancer starr_13701 Neighboring gene predicted gene, 34475 Neighboring gene microRNA 703 Neighboring gene STARR-seq mESC enhancer starr_13702 Neighboring gene RIKEN cDNA 1700010H22 gene Neighboring gene STARR-seq mESC enhancer starr_13703 Neighboring gene predicted gene, 24279 Neighboring gene predicted gene, 42122 Neighboring gene Bmp3 5' regulatory region Neighboring gene predicted gene, 34563 Neighboring gene predicted gene, 42123 Neighboring gene bone morphogenetic protein 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Cloning of a new testis-enriched gene C4orf22 and its role in cell cycle and apoptosis in mouse spermatogenic cells. Li H, et al. Mol Biol Rep, 2019 Apr. PMID 30820741
    2. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Miyata H, et al. Proc Natl Acad Sci U S A, 2016 Jul 12. PMID 27357688, Free PMC Article
    3. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
    4. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    5. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cilia- and flagella-associated protein 299
    Names
    uncharacterized protein C4orf22 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024614.2 → NP_001019785.1  cilia- and flagella-associated protein 299 isoform 1

      See identical proteins and their annotated locations for NP_001019785.1

      Status: VALIDATED

      Source sequence(s)
      AC132255, AC140359, AC147376, AC151721
      Consensus CDS
      CCDS19456.1
      UniProtKB/Swiss-Prot
      Q810M1
      Related
      ENSMUSP00000079208.4, ENSMUST00000080333.8
      Conserved Domains (1) summary
      pfam14713
      Location:13 → 232
      DUF4464; Domain of unknown function (DUF4464)

    2. NM_001417875.1 → NP_001404804.1  cilia- and flagella-associated protein 299 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC132255, AC140359, AC147376, AC151721

    3. NM_001417876.1 → NP_001404805.1  cilia- and flagella-associated protein 299 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC147376

    4. NM_001417877.1 → NP_001404806.1  cilia- and flagella-associated protein 299 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC147376

    5. NM_001417878.1 → NP_001404807.1  cilia- and flagella-associated protein 299 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC132255, AC140359, AC151721

    6. NM_001417879.1 → NP_001404808.1  cilia- and flagella-associated protein 299 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC147376

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      98476998..98949912
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006535280.5 → XP_006535343.1  cilia- and flagella-associated protein 299 isoform X2

      Conserved Domains (1) summary
      pfam14713
      Location:13 → 206
      DUF4464; Domain of unknown function (DUF4464)

    2. XM_006535279.5 → XP_006535342.1  cilia- and flagella-associated protein 299 isoform X1

      Conserved Domains (1) summary
      pfam14713
      Location:13 → 280
      DUF4464; Domain of unknown function (DUF4464)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q810M1.1 GenPept UniProtKB/Swiss-Prot:Q810M1

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