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    Zfp109 zinc finger protein 109 [ Mus musculus (house mouse) ]

    Gene ID: 56869, updated on 21-May-2024

    Summary

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    Official Symbol
    Zfp109provided by MGI
    Official Full Name
    zinc finger protein 109provided by MGI
    Primary source
    MGI:MGI:1929099
    See related
    Ensembl:ENSMUSG00000074283 AllianceGenome:MGI:1929099
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 1.5), limb E14.5 (RPKM 1.4) and 28 other tissues See more
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    Genomic context

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    See Zfp109 in Genome Data Viewer
    Location:
    7 A3; 7 10.27 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (23924763..23951764, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (24227795..24252339, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 114 Neighboring gene zinc finger protein 111 Neighboring gene zinc finger protein 108 Neighboring gene zinc finger protein 93 Neighboring gene predicted gene, 51471

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. Shannon M, et al. Genome Res, 2003 Jun. PMID 12743021, Free PMC Article
    2. Gene expression in the developing mouse retina by EST sequencing and microarray analysis. Mu X, et al. Nucleic Acids Res, 2001 Dec 15. PMID 11812828, Free PMC Article
    3. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
    4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Clone Names

    • MGC141452

    General protein information

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    Preferred Names
    zinc finger protein 109

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001420110.1 → NP_001407039.1  zinc finger protein 109 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC138791
      UniProtKB/TrEMBL
      Q9R166

    2. NM_001420111.1 → NP_001407040.1  zinc finger protein 109 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC138791
      Related
      ENSMUSP00000045498.7, ENSMUST00000037448.7

    3. NM_001420112.1 → NP_001407041.1  zinc finger protein 109 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC138791

    4. NM_020262.4 → NP_064658.1  zinc finger protein 109 isoform 1

      See identical proteins and their annotated locations for NP_064658.1

      Status: VALIDATED

      Source sequence(s)
      AC138791
      Consensus CDS
      CCDS39827.1
      UniProtKB/TrEMBL
      Q9R166
      Related
      ENSMUSP00000146043.2, ENSMUST00000206362.2
      Conserved Domains (3) summary
      COG5048
      Location:323 → 579
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:479 → 499
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 48
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      23924763..23951764 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242825.2 → XP_030098685.1  zinc finger protein 109 isoform X2

      UniProtKB/TrEMBL
      Q9R166
      Conserved Domains (3) summary
      COG5048
      Location:323 → 579
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:479 → 499
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 48
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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