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    Or13c7c olfactory receptor family 13 subfamily C member 7C [ Mus musculus (house mouse) ]

    Gene ID: 100040268, updated on 9-May-2024

    Summary

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    Official Symbol
    Or13c7cprovided by MGI
    Official Full Name
    olfactory receptor family 13 subfamily C member 7Cprovided by MGI
    Primary source
    MGI:MGI:1352684
    See related
    Ensembl:ENSMUSG00000111611 AllianceGenome:MGI:1352684
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Or37c; Olfr157; Olfr37c; Mor262-12
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Or13c7c in Genome Data Viewer
    Location:
    4 B1; 4 23.05 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (43834752..43837643, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (43834752..43837643, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 13 subfamily C member 7B Neighboring gene predicted gene, 30318 Neighboring gene olfactory receptor family 13 subfamily C member 7 Neighboring gene reversion-inducing-cysteine-rich protein with kazal motifs

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Promotor elements governing the clustered expression pattern of odorant receptor genes. Zhang YQ, et al. Mol Cell Neurosci, 2007 Sep. PMID 17656108
    2. Identification of a natural source for the OR37B ligand. Bautze V, et al. Chem Senses, 2014 Jan. PMID 24235213
    3. Brain targeting and glomerulus formation of two olfactory neuron populations expressing related receptor types. Conzelmann S, et al. Eur J Neurosci, 2001 Nov. PMID 11860457
    4. Local permutations in the glomerular array of the mouse olfactory bulb. Strotmann J, et al. J Neurosci, 2000 Sep 15. PMID 10995837, Free PMC Article
    5. The patch-like pattern of OR37 receptors is formed by turning off gene expression in non-appropriate areas. Strotmann J, et al. Mol Cell Neurosci, 2009 Aug. PMID 19463954

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (4)  1 citation

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    enables olfactory receptor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    olfactory receptor 157
    Names
    GA_x6K02T2N78B-16110014-16110970
    olfactory receptor 37c
    olfactory receptor MOR262-12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019475.3 → NP_062348.1  olfactory receptor 157

      See identical proteins and their annotated locations for NP_062348.1

      Status: VALIDATED

      Source sequence(s)
      AL773539
      Consensus CDS
      CCDS18114.1
      UniProtKB/TrEMBL
      Q9QZ20, Q9QZ21
      Related
      ENSMUSP00000150429.2, ENSMUST00000215442.2
      Conserved Domains (1) summary
      cd15430
      Location:25 → 300
      7tmA_OR13-like; olfactory receptor family 13 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      43834752..43837643 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537504.1 → XP_006537567.1  olfactory receptor 157 isoform X1

      See identical proteins and their annotated locations for XP_006537567.1

      UniProtKB/TrEMBL
      Q9QZ20, Q9QZ21
      Related
      ENSMUSP00000149336.2, ENSMUST00000214281.2
      Conserved Domains (1) summary
      cd15430
      Location:25 → 300
      7tmA_OR13-like; olfactory receptor family 13 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version

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