Antkmt adenine nucleotide translocase lysine methyltransferase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Antkmtprovided by RGD
Official Full Name: adenine nucleotide translocase lysine methyltransferaseprovided by RGD
Primary source: RGD:1306126
See related: Ensembl:ENSRNOG00000019684 AllianceGenome:RGD:1306126
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fam173a; RGD1306126
Summary: Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in peptidyl-lysine trimethylation; positive regulation of proton-transporting ATP synthase activity, rotational mechanism; and regulation of mitochondrial ATP synthesis coupled proton transport. Predicted to be located in mitochondrial membrane. Predicted to be integral component of membrane. Predicted to be active in mitochondrion. Orthologous to human ANTKMT (adenine nucleotide translocase lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 97.5), Kidney (RPKM 86.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (15316797..15320950, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (14812274..14814798, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (15160037..15161895, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein-lysine N-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-lysine N-methyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in methylation	IEA Inferred from Electronic Annotation more info
involved_in peptidyl-lysine trimethylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of proton-transporting ATP synthase activity, rotational mechanism	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of mitochondrial ATP synthesis coupled proton transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in mitochondrial membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: adenine nucleotide translocase lysine N-methyltransferase

Names: family with sequence similarity 173, member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001127447.1 → NP_001120919.1 adenine nucleotide translocase lysine N-methyltransferase

See identical proteins and their annotated locations for NP_001120919.1

Status: VALIDATED

Source sequence(s)

AW918226, BF284299

UniProtKB/TrEMBL

A6HD51, A6HD52, D4A1T7

Related

ENSRNOP00000026641.3, ENSRNOT00000026641.5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086028.1 Reference GRCr8

Range

15316797..15320950 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039085365.2 → XP_038941293.1 adenine nucleotide translocase lysine N-methyltransferase isoform X2
XM_039085364.2 → XP_038941292.1 adenine nucleotide translocase lysine N-methyltransferase isoform X1

UniProtKB/TrEMBL

A0A8I6A4W6, A6HD52

Related

ENSRNOP00000085813.1