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    Mif4gd MIF4G domain containing [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360659, updated on 5-Mar-2024

    Summary

    Official Symbol
    Mif4gdprovided by RGD
    Official Full Name
    MIF4G domain containingprovided by RGD
    Primary source
    RGD:1309685
    See related
    AllianceGenome:RGD:1309685
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309685
    Summary
    Predicted to enable identical protein binding activity; protein C-terminus binding activity; and translation activator activity. Predicted to be involved in regulation of translational initiation. Predicted to be located in Golgi apparatus and nucleolus. Predicted to be active in cytosol. Orthologous to human MIF4GD (MIF4G domain containing). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 172.2), Heart (RPKM 148.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mif4gd in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (101346120..101350584, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (100847168..100852166, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (104159170..104164166, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 3 Neighboring gene U6 spliceosomal RNA Neighboring gene mitochondrial ribosomal protein S7 Neighboring gene solute carrier family 25 member 19 Neighboring gene growth factor receptor bound protein 2 Neighboring gene high mobility group protein B1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in cap-dependent translational initiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of histone mRNA stem-loop binding complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    MIF4G domain-containing protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014122.1NP_001014144.1  MIF4G domain-containing protein

      See identical proteins and their annotated locations for NP_001014144.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079310
      UniProtKB/Swiss-Prot
      Q6AXU7
      UniProtKB/TrEMBL
      A6HKP3, A6HKP4
      Conserved Domains (1) summary
      cl02652
      Location:8179
      MIF4G; MIF4G domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      101346120..101350584 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006247723.4XP_006247785.1  MIF4G domain-containing protein isoform X1

      UniProtKB/TrEMBL
      A6HKP4