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    Nemp2 nuclear envelope integral membrane protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 503257, updated on 5-Mar-2024

    Summary

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    Symbol
    Nemp2provided by RGD
    Full Name
    nuclear envelope integral membrane protein 2provided by RGD
    Primary source
    RGD:1560421
    See related
    Ensembl:ENSRNOG00000012924 AllianceGenome:RGD:1560421
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem194b; RGD1560421
    Summary
    Predicted to be located in nuclear inner membrane. Predicted to be integral component of membrane. Predicted to be active in nuclear envelope. Orthologous to human NEMP2 (nuclear envelope integral membrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 63.4), Spleen (RPKM 45.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Nemp2 in Genome Data Viewer
    Location:
    9q22
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (56353233..56372586, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (48861252..48880565, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (53713598..53732858, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene BCL2 interacting protein 3, pseudogene 1 Neighboring gene major facilitator superfamily domain containing 6 Neighboring gene developmental pluripotency-associated protein 3-like Neighboring gene Ngfi-A binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nuclear envelope integral membrane protein 2
    Names
    transmembrane protein 194B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134642.1 → NP_001128114.1  nuclear envelope integral membrane protein 2 precursor

      See identical proteins and their annotated locations for NP_001128114.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473965
      UniProtKB/Swiss-Prot
      P0C8N6
      UniProtKB/TrEMBL
      A6INV9
      Related
      ENSRNOP00000032860.3, ENSRNOT00000029204.4
      Conserved Domains (1) summary
      pfam10225
      Location:142 → 389
      DUF2215; Uncharacterized conserved protein (DUF2215)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      56353233..56372586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039084132.2 → XP_038940060.1  nuclear envelope integral membrane protein 2 isoform X1

      Conserved Domains (1) summary
      pfam10225
      Location:142 → 376
      NEMP; NEMP family

    2. XM_039084133.2 → XP_038940061.1  nuclear envelope integral membrane protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I6G4K5, A6INW2
      Related
      ENSRNOP00000079039.1
      Conserved Domains (1) summary
      pfam10225
      Location:142 → 203
      NEMP; NEMP family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C8N6.1 GenPept UniProtKB/Swiss-Prot:P0C8N6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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