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    Mslnl mesothelin-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363554, updated on 29-Feb-2024

    Summary

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    Official Symbol
    Mslnlprovided by RGD
    Official Full Name
    mesothelin-likeprovided by RGD
    Primary source
    RGD:1561732
    See related
    Ensembl:ENSRNOG00000039339 AllianceGenome:RGD:1561732
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561732
    Summary
    Predicted to be involved in cell-matrix adhesion. Predicted to be located in membrane. Predicted to be active in cell surface. Orthologous to human MSLNL (mesothelin like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 5.1), Brain (RPKM 3.8) and 9 other tissues See more
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    Genomic context

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    See Mslnl in Genome Data Viewer
    Location:
    10q12
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15260084..15276190)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14755344..14771673)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15103047..15119427)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene G protein subunit gamma 13 Neighboring gene chromosome transmission fidelity factor 18 Neighboring gene RNA pseudouridine synthase domain containing 1 Neighboring gene mesothelin Neighboring gene cytosolic iron-sulfur assembly component 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell-matrix adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mesothelin-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15260084..15276190
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270020.1 → XP_063126090.1  mesothelin-like protein isoform X1

    2. XM_008767615.4 → XP_008765837.1  mesothelin-like protein isoform X2

      See identical proteins and their annotated locations for XP_008765837.1

      UniProtKB/TrEMBL
      D4AB62
      Related
      ENSRNOP00000057036.3
      Conserved Domains (1) summary
      pfam06060
      Location:1 → 584
      Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)

    3. XM_039087109.2 → XP_038943037.1  mesothelin-like protein isoform X3

      Conserved Domains (1) summary
      pfam06060
      Location:1 → 379
      Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
    Nucleotide Protein Strain
    Heading Accession and Version

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