U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Btg1c BTG anti-proliferation factor 1C [ Mus musculus (house mouse) ]

    Gene ID: 194735, updated on 22-Mar-2024

    Summary

    Official Symbol
    Btg1cprovided by MGI
    Official Full Name
    BTG anti-proliferation factor 1Cprovided by MGI
    Primary source
    MGI:MGI:3588265
    See related
    Ensembl:ENSMUSG00000121801 AllianceGenome:MGI:3588265
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Btg1-ps2; 4930430D24Rik
    Summary
    Predicted to enable enzyme binding activity. Predicted to be involved in several processes, including positive regulation of angiogenesis; positive regulation of endothelial cell differentiation; and positive regulation of fibroblast apoptotic process. Predicted to be active in cytoplasm and nucleus. Orthologous to human BTG1 (BTG anti-proliferation factor 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 7.1) See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Btg1c in Genome Data Viewer
    Location:
    X A3.3; X 22.29 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (37127076..37131991, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (38038199..38043114, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene reproductive homeobox 11, pseudogene 2 Neighboring gene BTG anti-proliferation factor 1B Neighboring gene reproductive homeobox 10 Neighboring gene STARR-seq mESC enhancer starr_47012 Neighboring gene reproductive homeobox 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in negative regulation of cell population proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    B cell translocation gene 1, anti-proliferative-like
    Names
    B cell translocation gene 1, anti-proliferative, pseudogene 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034856.3NP_001030028.1  B cell translocation gene 1, anti-proliferative-like

      See identical proteins and their annotated locations for NP_001030028.1

      Status: VALIDATED

      Source sequence(s)
      AL512346
      Consensus CDS
      CCDS53061.1
      UniProtKB/TrEMBL
      Q3V0X0
      Related
      ENSMUST00000248501.1
      Conserved Domains (1) summary
      pfam07742
      Location:1114
      BTG; BTG family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      37127076..37131991 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)