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    RPS25B ribosomal 40S subunit protein S25B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851045, updated on 6-Jun-2024

    Summary

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    Gene symbol
    RPS25B
    Gene description
    ribosomal 40S subunit protein S25B
    Primary source
    FungiDB:YLR333C
    Locus tag
    YLR333C
    See related
    SGD:S000004325; AllianceGenome:SGD:S000004325; VEuPathDB:YLR333C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic small ribosomal subunit. Orthologous to human RPS25 (ribosomal protein S25). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPS25B in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (795573..795899, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Glu Neighboring gene nucleoporin NUP2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Binding of a viral IRES to the 40S subunit occurs in two successive steps mediated by eS25. Walters B, et al. Nucleic Acids Res, 2020 Aug 20. PMID 32609821, Free PMC Article
    2. The gene for yeast ribosomal protein S31 contains an intron in the leader sequence. Nieuwint RT, et al. Curr Genet, 1985. PMID 2856436
    3. RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs. Landry DM, et al. Genes Dev, 2009 Dec 1. PMID 19952110, Free PMC Article
    4. Identification of protein N-terminal methyltransferases in yeast and humans. Webb KJ, et al. Biochemistry, 2010 Jun 29. PMID 20481588, Free PMC Article
    5. The Ccr4-Not complex monitors the translating ribosome for codon optimality. Buschauer R, et al. Science, 2020 Apr 17. PMID 32299921, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Binding of a viral IRES to the 40S subunit occurs in two successive steps mediated by eS25.
      Title: Binding of a viral IRES to the 40S subunit occurs in two successive steps mediated by eS25.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S25B
    NP_013437.1
    • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S25, no bacterial homolog; RPS25B has a paralog, RPS25A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      795573..795899 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182222.1 → NP_013437.1  TPA: ribosomal 40S subunit protein S25B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013437.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2TBM7, D6VYX4, P05758, P07282, P0C0T4
      UniProtKB/TrEMBL
      A0A6A5PTN7, A7A1L5, B3RHK7, C7GUA3, C8ZDU4, G2WJF3, N1NYM5
      Conserved Domains (1) summary
      COG4901
      Location:1 → 107
      RPS25; Ribosomal protein S25 [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C0T4.1

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