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    Mfap3l microfibrillar-associated protein 3-like [ Mus musculus (house mouse) ]

    Gene ID: 71306, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Mfap3lprovided by MGI
    Official Full Name
    microfibrillar-associated protein 3-likeprovided by MGI
    Primary source
    MGI:MGI:1918556
    See related
    Ensembl:ENSMUSG00000031647 AllianceGenome:MGI:1918556
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NYD-sp9; mKIAA0626; 4933428A15Rik; 5430405D20Rik
    Summary
    Predicted to be located in cell junction and nucleoplasm. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Is expressed in central nervous system. Orthologous to human MFAP3L (microfibril associated protein 3 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 23.6), frontal lobe adult (RPKM 7.6) and 7 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mfap3l in Genome Data Viewer
    Location:
    8 B3.1; 8 30.86 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (61085859..61129765)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (60632825..60676731)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53433 Neighboring gene STARR-seq mESC enhancer starr_21561 Neighboring gene predicted gene, 34730 Neighboring gene STARR-seq mESC enhancer starr_21563 Neighboring gene predicted gene, 53434 Neighboring gene predicted gene 45650

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    microfibrillar-associated protein 3-like

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177881.1 → NP_001171352.1  microfibrillar-associated protein 3-like isoform a precursor

      See identical proteins and their annotated locations for NP_001171352.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate 5' UTR exon compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
      Source sequence(s)
      AC121923, AK133407
      Consensus CDS
      CCDS22321.1
      UniProtKB/Swiss-Prot
      Q80TV6, Q8BJA9, Q9D3X9
      Related
      ENSMUSP00000124330.2, ENSMUST00000161702.8
      Conserved Domains (2) summary
      cd00096
      Location:64 → 139
      Ig; Immunoglobulin domain
      smart00410
      Location:55 → 142
      IG_like; Immunoglobulin like

    2. NM_001177882.1 → NP_001171353.1  microfibrillar-associated protein 3-like isoform a precursor

      See identical proteins and their annotated locations for NP_001171353.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has an alternate 5' UTR exon compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
      Source sequence(s)
      AC121923, AK016959
      Consensus CDS
      CCDS22321.1
      UniProtKB/Swiss-Prot
      Q80TV6, Q8BJA9, Q9D3X9
      Related
      ENSMUSP00000034066.4, ENSMUST00000034066.4
      Conserved Domains (2) summary
      cd00096
      Location:64 → 139
      Ig; Immunoglobulin domain
      smart00410
      Location:55 → 142
      IG_like; Immunoglobulin like

    3. NM_001293769.1 → NP_001280698.1  microfibrillar-associated protein 3-like isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate exon compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.
      Source sequence(s)
      AC121923
      Consensus CDS
      CCDS80877.1
      UniProtKB/Swiss-Prot
      Q9D3X9
      Related
      ENSMUSP00000124136.2, ENSMUST00000161421.2
      Conserved Domains (2) summary
      smart00410
      Location:7 → 39
      IG_like; Immunoglobulin like
      cl11960
      Location:7 → 39
      Ig; Immunoglobulin domain

    4. NM_027756.5 → NP_082032.1  microfibrillar-associated protein 3-like isoform a precursor

      See identical proteins and their annotated locations for NP_082032.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) and variants 2 and 3 encode the same isoform (a).
      Source sequence(s)
      AC121923, CJ132157
      Consensus CDS
      CCDS22321.1
      UniProtKB/Swiss-Prot
      Q80TV6, Q8BJA9, Q9D3X9
      Related
      ENSMUSP00000125139.2, ENSMUST00000160719.8
      Conserved Domains (2) summary
      cd00096
      Location:64 → 139
      Ig; Immunoglobulin domain
      smart00410
      Location:55 → 142
      IG_like; Immunoglobulin like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      61085859..61129765
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D3X9.1 GenPept UniProtKB/Swiss-Prot:Q9D3X9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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