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    Vmn2r22 vomeronasal 2, receptor 22 [ Mus musculus (house mouse) ]

    Gene ID: 546913, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Vmn2r22provided by MGI
    Official Full Name
    vomeronasal 2, receptor 22provided by MGI
    Primary source
    MGI:MGI:3647952
    See related
    Ensembl:ENSMUSG00000095486 AllianceGenome:MGI:3647952
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG546913
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See Vmn2r22 in Genome Data Viewer
    Location:
    6 F2; 6 58.66 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (123586717..123627594, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (123609758..123650635, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 22722 Neighboring gene vomeronasal 2, receptor, pseudogene 32 Neighboring gene predicted gene, 25065 Neighboring gene STARR-seq mESC enhancer starr_17277 Neighboring gene STARR-seq mESC enhancer starr_17278 Neighboring gene predicted gene, 18374 Neighboring gene STARR-seq mESC enhancer starr_17279 Neighboring gene vomeronasal 2, receptor 23 Neighboring gene predicted gene, 22724

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Olfactory receptors and signalling elements in the Grueneberg ganglion. Fleischer J, et al. J Neurochem, 2006 Jul. PMID 16805845
    2. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal receptor Vmn2r22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104637.1 → NP_001098107.1  vomeronasal receptor Vmn2r22 precursor

      Status: INFERRED

      Source sequence(s)
      AC140334
      Consensus CDS
      CCDS51900.1
      UniProtKB/TrEMBL
      E9PYE6, E9Q7S8
      Related
      ENSMUSP00000132043.2, ENSMUST00000170808.3
      Conserved Domains (4) summary
      cd06365
      Location:37 → 509
      PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam00003
      Location:604 → 838
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:82 → 394
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:519 → 569
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      123586717..123627594 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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