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    CG3609 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33421, updated on 10-May-2024

    Summary

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    Official Symbol
    CG3609provided by FlyBase
    Primary source
    FLYBASE:FBgn0031418
    Locus tag
    Dmel_CG3609
    See related
    AllianceGenome:FB:FBgn0031418
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT12127; Dmel\CG3609
    Summary
    Predicted to enable oxidoreductase activity. Is expressed in adult head and adult heart. Orthologous to human DHDH (dihydrodiol dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG3609 in Genome Data Viewer
    Location:
    22E1-22E1; 2-6 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2372455..2374627, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2372455..2374627, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene AXIN1 up-regulated 1 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44982 Neighboring gene uncharacterized protein Neighboring gene Ataxin 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Introgression in the Drosophila subobscura--D. Madeirensis sister species: evidence of gene flow in nuclear genes despite mitochondrial differentiation. Herrig DK, et al. Evolution, 2014 Mar. PMID 24152112, Free PMC Article
    2. The expression pattern of the Drosophila vesicular glutamate transporter: a marker protein for motoneurons and glutamatergic centers in the brain. Mahr A, et al. Gene Expr Patterns, 2006 Mar. PMID 16378756
    3. New comparative genomics approach reveals a conserved health span signature across species. Antosh M, et al. Aging (Albany NY), 2011 Jun. PMID 21775776, Free PMC Article
    4. Ancient Male Recombination Shaped Genetic Diversity of Neo-Y Chromosome in Drosophila albomicans. Satomura K, et al. Mol Biol Evol, 2016 Feb. PMID 26494844
    5. Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. Yoon WH, et al. Neuron, 2017 Jan 4. PMID 28017472, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables D-xylose 1-dehydrogenase (NADP+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-xylose catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3609-PA
    CG3609-PB
    CG3609-PC
    NP_001188684.1
    NP_001259931.1
    NP_608675.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2372455..2374627 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134831.3 → NP_608675.1  uncharacterized protein Dmel_CG3609, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608675.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQB4
      Related
      FBpp0077468
      Conserved Domains (3) summary
      COG0673
      Location:5 → 292
      MviM; Predicted dehydrogenase [General function prediction only]
      pfam01408
      Location:5 → 123
      GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold
      cl21649
      Location:138 → 198
      GFO_IDH_MocA_C; Oxidoreductase family, C-terminal alpha/beta domain

    2. NM_001273002.1 → NP_001259931.1  uncharacterized protein Dmel_CG3609, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259931.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQB4
      Conserved Domains (3) summary
      COG0673
      Location:5 → 292
      MviM; Predicted dehydrogenase [General function prediction only]
      pfam01408
      Location:5 → 123
      GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold
      cl21649
      Location:138 → 198
      GFO_IDH_MocA_C; Oxidoreductase family, C-terminal alpha/beta domain

    3. NM_001201755.2 → NP_001188684.1  uncharacterized protein Dmel_CG3609, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188684.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQB4
      Conserved Domains (3) summary
      COG0673
      Location:5 → 292
      MviM; Predicted dehydrogenase [General function prediction only]
      pfam01408
      Location:5 → 123
      GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold
      cl21649
      Location:138 → 198
      GFO_IDH_MocA_C; Oxidoreductase family, C-terminal alpha/beta domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQB4 Q9VQB4

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