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    CG11594 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38473, updated on 10-May-2024

    Summary

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    Official Symbol
    CG11594provided by FlyBase
    Primary source
    FLYBASE:FBgn0035484
    Locus tag
    Dmel_CG11594
    See related
    AllianceGenome:FB:FBgn0035484
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11594
    Summary
    Predicted to enable D-ribulokinase activity. Involved in response to endoplasmic reticulum stress. Orthologous to human FGGY (FGGY carbohydrate kinase domain containing). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG11594 in Genome Data Viewer
    Location:
    64A4-64A4; 3-10 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4022700..4026011, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4022974..4026011, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Forkhead box L1 Neighboring gene Mitochondrial E3 ubiquitin protein ligase 1 Neighboring gene Gustatory receptor 64a Neighboring gene Gustatory receptor 64c Neighboring gene Gustatory receptor 64b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila. Beumer KJ, et al. G3 (Bethesda), 2013 Oct 3. PMID 23979928, Free PMC Article
    2. Gustatory and metabolic perception of nutrient stress in Drosophila. Linford NJ, et al. Proc Natl Acad Sci U S A, 2015 Feb 24. PMID 25675472, Free PMC Article
    3. Sugar receptors in Drosophila. Slone J, et al. Curr Biol, 2007 Oct 23. PMID 17919910, Free PMC Article
    4. Drosophila Gr64e mediates fatty acid sensing via the phospholipase C pathway. Kim H, et al. PLoS Genet, 2018 Feb. PMID 29420533, Free PMC Article
    5. Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genes. Chow CY, et al. Proc Natl Acad Sci U S A, 2013 May 28. PMID 23667151, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables D-ribulokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables D-ribulokinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphotransferase activity, alcohol group as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pentose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to endoplasmic reticulum stress HMP PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11594-PA
    CG11594-PC
    CG11594-PD
    CG11594-PE
    NP_001261391.1
    NP_647848.2
    NP_728918.1
    NP_728919.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4022700..4026011 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168046.3 → NP_728918.1  uncharacterized protein Dmel_CG11594, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728918.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95T84, Q9VZJ8
      Related
      FBpp0073140
      Conserved Domains (2) summary
      cd07782
      Location:5 → 540
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases
      TIGR01315
      Location:6 → 540
      5C_CHO_kinase; FGGY-family pentulose kinase

    2. NM_168047.2 → NP_728919.1  uncharacterized protein Dmel_CG11594, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728919.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95T84, Q9VZJ8
      Related
      FBpp0073139
      Conserved Domains (2) summary
      cd07782
      Location:5 → 540
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases
      TIGR01315
      Location:6 → 540
      5C_CHO_kinase; FGGY-family pentulose kinase

    3. NM_001274462.1 → NP_001261391.1  uncharacterized protein Dmel_CG11594, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261391.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95T84, Q9VZJ8
      Conserved Domains (2) summary
      cd07782
      Location:5 → 540
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases
      TIGR01315
      Location:6 → 540
      5C_CHO_kinase; FGGY-family pentulose kinase

    4. NM_139591.4 → NP_647848.2  uncharacterized protein Dmel_CG11594, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647848.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95T84, Q9VZJ8
      Conserved Domains (2) summary
      cd07782
      Location:5 → 540
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases
      TIGR01315
      Location:6 → 540
      5C_CHO_kinase; FGGY-family pentulose kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95T84 Q95T84
    Q9VZJ8 Q9VZJ8

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