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    Oser1 oxidative stress responsive serine rich 1 [ Mus musculus (house mouse) ]

    Gene ID: 66680, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Oser1provided by MGI
    Official Full Name
    oxidative stress responsive serine rich 1provided by MGI
    Primary source
    MGI:MGI:1913930
    See related
    Ensembl:ENSMUSG00000035399 AllianceGenome:MGI:1913930
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Perit1; 3230401D17Rik
    Summary
    Predicted to be involved in cellular response to hydrogen peroxide. Is expressed in cerebral cortex ventricular layer. Orthologous to human OSER1 (oxidative stress responsive serine rich 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 70.1), placenta adult (RPKM 16.5) and 21 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Oser1 in Genome Data Viewer
    Location:
    2 H3; 2 84.26 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (163247742..163266422, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (163405822..163419470, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:163054873-163055132 Neighboring gene TOX high mobility group box family member 2 Neighboring gene VISTA enhancer mm1646 Neighboring gene junctophilin 2 Neighboring gene predicted gene, 35750 Neighboring gene STARR-seq mESC enhancer starr_06306 Neighboring gene STARR-seq mESC enhancer starr_06307 Neighboring gene STARR-positive B cell enhancer ABC_E2651 Neighboring gene RIKEN cDNA 2900093K20 gene Neighboring gene STARR-positive B cell enhancer ABC_E1608 Neighboring gene ganglioside-induced differentiation-associated protein 1-like 1 Neighboring gene STARR-seq mESC enhancer starr_06310 Neighboring gene RIKEN cDNA 2310001K24 gene Neighboring gene STARR-positive B cell enhancer ABC_E4516 Neighboring gene fat storage-inducing transmembrane protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Cardiac myocyte gene expression profiling during H2O2-induced apoptosis. Clerk A, et al. Physiol Genomics, 2007 Apr 24. PMID 17148688
    2. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Sansom SN, et al. PLoS Genet, 2009 Jun. PMID 19521500, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to hydrogen peroxide IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular response to hydrogen peroxide ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    oxidative stress-responsive serine-rich protein 1
    Names
    oxidative stress-responsive protein 1
    peroxide-inducible transcript 1 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418537.1 → NP_001405466.1  oxidative stress-responsive serine-rich protein 1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL589876
      UniProtKB/Swiss-Prot
      A2A477, Q3U5N3, Q9CXJ2, Q9D722, Q9D9G1
      Related
      ENSMUSP00000131932.2, ENSMUST00000104954.9

    2. NM_001418538.1 → NP_001405467.1  oxidative stress-responsive serine-rich protein 1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL589876
      UniProtKB/Swiss-Prot
      A2A477, Q3U5N3, Q9CXJ2, Q9D722, Q9D9G1

    3. NM_001418539.1 → NP_001405468.1  oxidative stress-responsive serine-rich protein 1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL589876
      UniProtKB/Swiss-Prot
      A2A477, Q3U5N3, Q9CXJ2, Q9D722, Q9D9G1

    4. NM_001418540.1 → NP_001405469.1  oxidative stress-responsive serine-rich protein 1 isoform b

      Status: VALIDATED

      Source sequence(s)
      AL589876

    5. NM_025699.3 → NP_079975.2  oxidative stress-responsive serine-rich protein 1 isoform a

      See identical proteins and their annotated locations for NP_079975.2

      Status: VALIDATED

      Source sequence(s)
      AL589876
      Consensus CDS
      CCDS17009.1
      UniProtKB/Swiss-Prot
      A2A477, Q3U5N3, Q9CXJ2, Q9D722, Q9D9G1
      UniProtKB/TrEMBL
      Q3UT72
      Related
      ENSMUSP00000039190.4, ENSMUST00000046908.10
      Conserved Domains (1) summary
      pfam05604
      Location:1 → 175
      DUF776; Protein of unknown function (DUF776)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      163247742..163266422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D722.1 GenPept UniProtKB/Swiss-Prot:Q9D722

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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