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    MYB15 myb domain protein 15 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821904, updated on 7-Sep-2023

    Summary

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    Gene symbol
    MYB15
    Gene description
    myb domain protein 15
    Primary source
    Araport:AT3G23250
    Locus tag
    AT3G23250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMYB15; ATY19; myb domain protein 15; MYB DOMAIN PROTEIN 15
    Summary
    Member of the R2R3 factor gene family.
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    Genomic context

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    See MYB15 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (8309209..8310910)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ethylene response factor 1 Neighboring gene uncharacterized protein Neighboring gene tRNA dimethylallyltransferase Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SG2-Type R2R3-MYB Transcription Factor MYB15 Controls Defense-Induced Lignification and Basal Immunity in Arabidopsis. Chezem WR, et al. Plant Cell, 2017 Aug. PMID 28733420, Free PMC Article
    2. A wheat aminocyclopropane-1-carboxylate oxidase gene, TaACO1, negatively regulates salinity stress in Arabidopsis thaliana. Chen D, et al. Plant Cell Rep, 2014 Nov. PMID 25048023
    3. Transgenic expression of MYB15 confers enhanced sensitivity to abscisic acid and improved drought tolerance in Arabidopsis thaliana. Ding Z, et al. J Genet Genomics, 2009 Jan. PMID 19161942
    4. Phosphorylation of the transcriptional repressor MYB15 by mitogen-activated protein kinase 6 is required for freezing tolerance in Arabidopsis. Kim SH, et al. Nucleic Acids Res, 2017 Jun 20. PMID 28510716, Free PMC Article
    5. A R2R3 type MYB transcription factor is involved in the cold regulation of CBF genes and in acquired freezing tolerance. Agarwal M, et al. J Biol Chem, 2006 Dec 8. PMID 17015446

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the Arabidopsis thaliana SG2-type R2R3-MYB transcription factor MYB15 is a regulator of defense-induced lignification and basal immunity.
      Title: SG2-Type R2R3-MYB Transcription Factor MYB15 Controls Defense-Induced Lignification and Basal Immunity in Arabidopsis.
    2. MPK6-mediated regulation of MYB15 plays an important role in cold stress signaling in Arabidopsis.
      Title: Phosphorylation of the transcriptional repressor MYB15 by mitogen-activated protein kinase 6 is required for freezing tolerance in Arabidopsis.
    3. Data show that constitutive expression of aminocyclopropane-1-carboxylate oxidase gene, TaACO1 in Arabidopsis increased AtMYB15 expression.
      Title: A wheat aminocyclopropane-1-carboxylate oxidase gene, TaACO1, negatively regulates salinity stress in Arabidopsis thaliana.
    4. transgenic expression of MYB15, encoding a R2R3 MYB transcription factor in Arabidopsis thaliana, conferred hypersensitivity to exogenous abscisic acid (ABA) and improved tolerance to drought and salt stresses
      Title: Transgenic expression of MYB15 confers enhanced sensitivity to abscisic acid and improved drought tolerance in Arabidopsis thaliana.
    5. myb15 mutant plants show increased tolerance to freezing stress whereas its overexpression reduces freezing tolerance
      Title: A R2R3 type MYB transcription factor is involved in the cold regulation of CBF genes and in acquired freezing tolerance.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001035670.1
    NM_113226.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to cold IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    myb domain protein 15
    NP_001030747.1
    • myb domain protein 15 (MYB15); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 13 (TAIR:AT1G06180.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_188966.1
    • myb domain protein 15 (MYB15); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 14 (TAIR:AT2G31180.1); Has 9082 Blast hits to 8389 proteins in 525 species: Archae - 0; Bacteria - 0; Metazoa - 803; Fungi - 506; Plants - 5968; Viruses - 4; Other Eukaryotes - 1801 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8309209..8310910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113226.5 → NP_188966.1  myb domain protein 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188966.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49744, Q39260, Q9LTC4
      UniProtKB/TrEMBL
      A0A178V7L7, A0A5S9XEW2
      Conserved Domains (1) summary
      PLN03212
      Location:5 → 191
      PLN03212; Transcription repressor MYB5; Provisional

    2. NM_001035670.1 → NP_001030747.1  myb domain protein 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030747.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4J2X8
      Conserved Domains (2) summary
      smart00717
      Location:10 → 57
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam00249
      Location:10 → 55
      Myb_DNA-binding; Myb-like DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LTC4.1

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