pdgy pudgy [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: pdgyprovided by FlyBase
Official Full Name: pudgyprovided by FlyBase
Primary source: FLYBASE:FBgn0027601
Locus tag: Dmel_CG9009
See related: AllianceGenome:FB:FBgn0027601
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:GH02901; CG9009; Dmel\CG9009; Pdgy
Summary: Enables long-chain fatty acid-CoA ligase activity. Involved in fatty-acyl-CoA biosynthetic process; long-chain fatty acid metabolic process; and triglyceride catabolic process. Located in mitochondrion. Is expressed in several structures, including extended germ band embryo; fat body; germ layer; presumptive embryonic/larval system; and stage 5 embryo. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: 13A1-13A1; 1-49 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (14933670..14953532, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (14827703..14847565, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables long-chain fatty acid-CoA ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables long-chain fatty acid-CoA ligase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in fatty-acyl-CoA biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in fatty-acyl-CoA biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in long-chain fatty acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in long-chain fatty acid metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in triglyceride catabolic process	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: pudgy

Names: CG9009-PA; CG9009-PB; CG9009-PC; CG9009-PD; long chain fatty acid CoA ligase; pdgy-PA; pdgy-PB; pdgy-PC; pdgy-PD

NP_001188590.1

EC 6.2.1.3

NP_001245673.1

EC 6.2.1.3

NP_001285257.1

EC 6.2.1.3

NP_572988.1

EC 6.2.1.3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_004354.4 Reference assembly

Range

14933670..14953532 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001201661.2 → NP_001188590.1 pudgy, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001188590.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9VXZ8, Q9Y158

Conserved Domains (2) summary

cd05911
Location:99 → 587

Firefly_Luc_like; Firefly luciferase of light emitting insects and 4-Coumarate-CoA Ligase (4CL)

COG0318
Location:77 → 595

CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
NM_001298328.1 → NP_001285257.1 pudgy, isoform D [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001285257.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9VXZ8, Q9Y158

Conserved Domains (2) summary

cd05911
Location:99 → 587

Firefly_Luc_like; Firefly luciferase of light emitting insects and 4-Coumarate-CoA Ligase (4CL)

COG0318
Location:77 → 595

CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
NM_001258744.1 → NP_001245673.1 pudgy, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001245673.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9VXZ8, Q9Y158

Conserved Domains (2) summary

cd05911
Location:99 → 587

Firefly_Luc_like; Firefly luciferase of light emitting insects and 4-Coumarate-CoA Ligase (4CL)

COG0318
Location:77 → 595

CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
NM_132760.5 → NP_572988.1 pudgy, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_572988.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9VXZ8, Q9Y158

Related

FBpp0073789

Conserved Domains (2) summary

cd05911
Location:99 → 587

Firefly_Luc_like; Firefly luciferase of light emitting insects and 4-Coumarate-CoA Ligase (4CL)

COG0318
Location:77 → 595

CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]