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    U1A spliceosomal protein U1A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819371, updated on 7-Sep-2023

    Summary

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    Gene symbol
    U1A
    Gene description
    spliceosomal protein U1A
    Primary source
    Araport:AT2G47580
    Locus tag
    AT2G47580
    See related
    TAIR:AT2G47580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    spliceosomal protein U1A; T30B22.12; U1SNRNP-SPECIFIC PROTEIN
    Summary
    encodes spliceosomal protein U1A
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    Genomic context

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    See U1A in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (19517187..19518913)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene ncRNA Neighboring gene 60S ribosomal protein L18 Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene photolyase/blue-light receptor 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spliceosomal protein U1A is involved in alternative splicing and salt stress tolerance in Arabidopsis thaliana. Gu J, et al. Nucleic Acids Res, 2018 Feb 28. PMID 29228330, Free PMC Article
    2. Molecular characterization of the spliceosomal proteins U1A and U2B" from higher plants. Simpson GG, et al. EMBO J, 1995 Sep 15. PMID 7556097, Free PMC Article
    3. Expression of Arabidopsis SR-like splicing proteins confers salt tolerance to yeast and transgenic plants. Forment J, et al. Plant J, 2002 Jun. PMID 12047626
    4. Evolutionary conservation of minor U12-type spliceosome between plants and humans. Lorkovic ZJ, et al. RNA, 2005 Jul. PMID 15987817, Free PMC Article
    5. High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. Koroleva OA, et al. Plant J, 2005 Jan. PMID 15610358

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A critical role for the AtU1A spliceosomal protein in regulating alternative splicing and in determining salt tolerance.
      Title: Spliceosomal protein U1A is involved in alternative splicing and salt stress tolerance in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_130326.3

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U1 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U1 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleolus HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    spliceosomal protein U1A
    NP_182280.1
    • spliceosomal protein U1A (U1A); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: response to salt stress, nuclear mRNA splicing, via spliceosome; LOCATED IN: nucleolus, nucleus, U1 snRNP; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: U2 small nuclear ribonucleoprotein B (TAIR:AT2G30260.1); Has 2473 Blast hits to 2417 proteins in 290 species: Archae - 0; Bacteria - 37; Metazoa - 1259; Fungi - 517; Plants - 407; Viruses - 1; Other Eukaryotes - 252 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      19517187..19518913
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130326.3 → NP_182280.1  spliceosomal protein U1A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182280.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39244
      UniProtKB/TrEMBL
      A0A178VZ67, A0A5S9X7T5
      Conserved Domains (2) summary
      cd12246
      Location:19 → 96
      RRM1_U1A_like; RNA recognition motif 1 (RRM1) found in the U1A/U2B"/SNF protein family
      cd12247
      Location:175 → 246
      RRM2_U1A_like; RNA recognition motif 2 (RRM2) found in the U1A/U2B"/SNF protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39244.1

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