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    AT5G04120 Phosphoglycerate mutase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830290, updated on 7-Sep-2023

    Summary

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    Gene symbol
    AT5G04120
    Gene description
    Phosphoglycerate mutase family protein
    Primary source
    Araport:AT5G04120
    Locus tag
    AT5G04120
    See related
    TAIR:AT5G04120
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F21E1.40; F21E1_40
    Summary
    Encodes a cofactor-dependent phosphoglycerate mutase (dPGM) - like protein with phosphoserine phosphatase activity that may be responsible for serine anabolism.
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    Genomic context

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    See AT5G04120 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (1119937..1121813)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene cysteine-rich TM module stress tolerance protein Neighboring gene histidine-tRNA ligase Neighboring gene DNA GYRASE B3 Neighboring gene DNA GYRASE B2 Neighboring gene glutamate synthase 1 Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene Nucleotide-sugar transporter family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Discovery and analysis of cofactor-dependent phosphoglycerate mutase homologs as novel phosphoserine phosphatases in Hydrogenobacter thermophilus. Chiba Y, et al. J Biol Chem, 2012 Apr 6. PMID 22337887, Free PMC Article
    2. Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Saracco SA, et al. Plant J, 2009 Jul. PMID 19292762, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_120494.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables L-phosphoserine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within D-serine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within L-serine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Phosphoglycerate mutase family protein
    NP_196032.1
    • Phosphoglycerate mutase family protein; FUNCTIONS IN: catalytic activity; INVOLVED IN: metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: root; CONTAINS InterPro DOMAIN/s: Histidine phosphatase superfamily, clade-1 (InterPro:IPR013078), Phosphoglycerate/bisphosphoglycerate mutase, active site (InterPro:IPR001345); BEST Arabidopsis thaliana protein match is: Phosphoglycerate mutase family protein (TAIR:AT3G50520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1119937..1121813
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120494.4 → NP_196032.1  Phosphoglycerate mutase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196032.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KI56, Q8GYJ6, Q9FYE8
      UniProtKB/TrEMBL
      A0A178UPS1, A0A5S9Y191, A0A7G2FC93
      Conserved Domains (1) summary
      pfam00300
      Location:27 → 219
      His_Phos_1; Histidine phosphatase superfamily (branch 1)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4KI56.1

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