GG1 Ggamma-subunit 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: GG1
Gene description: Ggamma-subunit 1
Primary source: Araport:AT3G63420
Locus tag: AT3G63420
See related: TAIR:AT3G63420
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AGG1; ATAGG1; Ggamma-subunit 1; HETEROTRIMERIC G PROTEIN GAMMA-SUBUNIT
Summary: heterotrimeric G protein gamma-subunit (AGG1) mRNA
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Genomic context

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See GG1 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 4

Sequence:: Chromosome: 3; NC_003074.8 (23417249..23419024)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The fact that AGG1 and AGG2 are functionally interchangeable in some pathways implies that, at least for those pathways, signaling specificity resides in the distinctive spatiotemporal expression patterns exhibited by each gamma subunit.
Title: Signaling specificity provided by the Arabidopsis thaliana heterotrimeric G-protein γ subunits AGG1 and AGG2 is partially but not exclusively provided through transcriptional regulation.
AGG1, AGG2 and AGB1 control the immune responses and the regulation of cell wall composition.
Title: Arabidopsis heterotrimeric G-protein regulates cell wall defense and resistance to necrotrophic fungi.
GPA1, AGB1, AGG and RGS1 are involved in glucose attenuation of auxin-mediated lateral root formation.
Title: Glucose attenuation of auxin-mediated bimodality in lateral root formation is partly coupled by the heterotrimeric G protein complex.
Posttranslational modification of AGG1 is required for plasma membrane targeting.
Title: Dual lipid modification of Arabidopsis Ggamma-subunits is required for efficient plasma membrane targeting.
This research provides evidence of the functional association of alpha and beta with the gamma subunits in Arabidopsis, while also suggesting that plasma membrane localization may be critical for function of plant heterotrimeric G proteins.
Title: Over-expression of a truncated Arabidopsis thaliana heterotrimeric G protein gamma subunit results in a phenotype similar to alpha and beta subunit knockouts.
the Gbetagamma complex serves a signaling function in the ER independent of its function in the Galphabetagamma heterotrimer
Title: Heterotrimeric G protein signaling in the Arabidopsis unfolded protein response.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_116207.3

Supported by ESTs:

NM_180410.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables GTP binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within acropetal auxin transport	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within defense response to fungus	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within lateral root development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein palmitoylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein prenylation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within seed germination	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
part_of heterotrimeric G-protein complex	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	ISM Inferred from Sequence Model more info
located_in plasma membrane	HDA more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Ggamma-subunit 1

NP_567147.1

Ggamma-subunit 1 (GG1); FUNCTIONS IN: GTP binding; INVOLVED IN: defense response to fungus, incompatible interaction, acropetal auxin transport, seed germination, lateral root development; LOCATED IN: plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: G-protein gamma subunit 2 (TAIR:AT3G22942.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NP_850741.1

Ggamma-subunit 1 (GG1); FUNCTIONS IN: GTP binding; INVOLVED IN: defense response to fungus, incompatible interaction, acropetal auxin transport, seed germination, lateral root development; LOCATED IN: plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: G-protein gamma subunit 2 (TAIR:AT3G22942.1); Has 72 Blast hits to 72 proteins in 13 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 72; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).