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    Vmn2r10 vomeronasal 2, receptor 10 [ Mus musculus (house mouse) ]

    Gene ID: 22307, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Vmn2r10provided by MGI
    Official Full Name
    vomeronasal 2, receptor 10provided by MGI
    Primary source
    MGI:MGI:1316730
    See related
    Ensembl:ENSMUSG00000067010 AllianceGenome:MGI:1316730
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    VR16; V2r16
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Vmn2r10 in Genome Data Viewer
    Location:
    5 F; 5 53.24 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (109141278..109154337, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (108995539..109006436, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene general transcription factor IIH, polypeptide 3 pseudogene Neighboring gene coiled-coil domain containing 77 pseudogene Neighboring gene STARR-seq mESC enhancer starr_13913 Neighboring gene predicted gene 5871 Neighboring gene STARR-seq mESC enhancer starr_13914 Neighboring gene vomeronasal 2, receptor 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A multigene family encoding a diverse array of putative pheromone receptors in mammals. Matsunami H, et al. Cell, 1997 Aug 22. PMID 9288756
    2. Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Zambrowicz BP, et al. Nature, 1998 Apr 9. PMID 9560157
    3. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2, receptor, 16
    Names
    vomeronasal organ family 2, receptor, 16
    vomeronasal receptor Vmn2r10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001385035.1 → NP_001371964.1  vomeronasal 2, receptor, 16 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC133456
      Conserved Domains (3) summary
      cd15283
      Location:579 → 829
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:45 → 498
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam07562
      Location:506 → 559
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. NM_009491.4 → NP_033517.3  vomeronasal 2, receptor, 16 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC133456
      Consensus CDS
      CCDS51596.1
      UniProtKB/TrEMBL
      K7N621
      Related
      ENSMUSP00000078162.4, ENSMUST00000079163.5
      Conserved Domains (3) summary
      cd06365
      Location:40 → 498
      PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam00003
      Location:594 → 828
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam07562
      Location:508 → 559
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RNA

    1. NR_169559.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC133456

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      109141278..109154337 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030254368.1 → XP_030110228.1  vomeronasal 2, receptor, 16 isoform X1

      Conserved Domains (3) summary
      cd15283
      Location:582 → 832
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:508 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cd06365
      Location:45 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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