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    Tas2r119 taste receptor, type 2, member 119 [ Mus musculus (house mouse) ]

    Gene ID: 57254, updated on 30-Apr-2024

    Summary

    Official Symbol
    Tas2r119provided by MGI
    Official Full Name
    taste receptor, type 2, member 119provided by MGI
    Primary source
    MGI:MGI:2681253
    See related
    Ensembl:ENSMUSG00000045267 AllianceGenome:MGI:2681253
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    T2r19; mGR19; mt2r19; Tas2r19
    Summary
    Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in circumvallate papilla; colon; duodenum; and jejunum. Orthologous to human TAS2R1 (taste 2 receptor member 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See Tas2r119 in Genome Data Viewer
    Location:
    15 B3.1; 15 13.02 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (32177435..32178440)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (32177289..32178294)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53869 Neighboring gene predicted gene, 46522 Neighboring gene WD repeat domain 75 pseudogene Neighboring gene STARR-seq mESC enhancer starr_38295 Neighboring gene STARR-seq mESC enhancer starr_38296 Neighboring gene predicted gene, 32499 Neighboring gene STARR-seq mESC enhancer starr_38297 Neighboring gene small nucleolar RNA, C/D box 123 Neighboring gene small nucleolar RNA host gene 18 Neighboring gene STARR-seq mESC enhancer starr_38298 Neighboring gene sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A Neighboring gene predicted gene, 53870

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables bitter taste receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables bitter taste receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables taste receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    taste receptor type 2 member 119
    Names
    T2R119
    candidate taste receptor T2R19
    taste receptor type 2 member 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020503.3NP_065249.3  taste receptor type 2 member 119

      Status: VALIDATED

      Source sequence(s)
      AC137123
      Consensus CDS
      CCDS49590.1
      UniProtKB/TrEMBL
      A2VCK4, G3X986
      Related
      ENSMUSP00000050277.3, ENSMUST00000057633.4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      32177435..32178440
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)