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    Mcmbp minichromosome maintenance complex binding protein [ Mus musculus (house mouse) ]

    Gene ID: 210711, updated on 30-Apr-2024

    Summary

    Official Symbol
    Mcmbpprovided by MGI
    Official Full Name
    minichromosome maintenance complex binding proteinprovided by MGI
    Primary source
    MGI:MGI:1920977
    See related
    Ensembl:ENSMUSG00000048170 AllianceGenome:MGI:1920977
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MCM-BP; 1110007A13Rik
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in DNA-dependent DNA replication and sister chromatid cohesion. Predicted to act upstream of or within DNA replication and cell division. Predicted to be located in cell junction; cytosol; and nucleoplasm. Predicted to be part of MCM complex. Orthologous to human MCMBP (minichromosome maintenance complex binding protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 21.9), thymus adult (RPKM 17.2) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mcmbp in Genome Data Viewer
    Location:
    7 F3; 7 70.41 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (128298165..128342153, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (128696441..128740429, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1743 Neighboring gene mitochondrial ribosomal protein S36 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E3756 Neighboring gene inositol polyphosphate-5-phosphatase F Neighboring gene pentatricopeptide repeat domain 3 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E3757 Neighboring gene Sec23 interacting protein Neighboring gene STARR-seq mESC enhancer starr_20212 Neighboring gene STARR-seq mESC enhancer starr_20213 Neighboring gene STARR-seq mESC enhancer starr_20214 Neighboring gene predicted gene, 39093

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC36596

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA-templated DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in DNA-templated DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sister chromatid cohesion ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of MCM complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mini-chromosome maintenance complex-binding protein
    Names
    MCM (minichromosome maintenance deficient) binding protein
    MCM-binding protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145955.3NP_666067.1  mini-chromosome maintenance complex-binding protein

      See identical proteins and their annotated locations for NP_666067.1

      Status: PROVISIONAL

      Source sequence(s)
      AC122767, AC136741
      Consensus CDS
      CCDS40153.1
      UniProtKB/Swiss-Prot
      D3Z3G1, Q8R3C0
      UniProtKB/TrEMBL
      H9KV04
      Related
      ENSMUSP00000062843.8, ENSMUST00000057557.14
      Conserved Domains (1) summary
      pfam09739
      Location:36628
      MCM_bind; Mini-chromosome maintenance replisome factor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      128298165..128342153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)