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    ftsh10 FTSH protease 10 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837265, updated on 15-Oct-2023

    Summary

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    Gene symbol
    ftsh10
    Gene description
    FTSH protease 10
    Primary source
    Araport:AT1G07510
    Locus tag
    AT1G07510
    See related
    TAIR:AT1G07510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F22G5.10; F22G5_10; FTSH protease 10
    Summary
    encodes an FtsH protease that is localized to the mitochondrion
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    Genomic context

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    See ftsh10 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (2304435..2312399)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Transcription factor IIA, alpha/beta subunit Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ROTUNDIFOLIA like 3 Neighboring gene uncharacterized protein Neighboring gene GRAS family transcription factor Neighboring gene SCARECROW-like 14 Neighboring gene TRF-like 2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of high molecular weight complexes formed by matrix AAA proteases and prohibitins in mitochondria of Arabidopsis thaliana. Piechota J, et al. J Biol Chem, 2010 Apr 23. PMID 20172857, Free PMC Article
    2. Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes. Sakamoto W, et al. Plant Cell, 2003 Dec. PMID 14630971, Free PMC Article
    3. New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy. Peltier JB, et al. J Biol Chem, 2004 Nov 19. PMID 15322131
    4. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_100625.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast thylakoid membrane HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    FTSH protease 10
    NP_172231.2
    • FTSH protease 10 (ftsh10); FUNCTIONS IN: in 6 functions; INVOLVED IN: proteolysis, protein catabolic process; LOCATED IN: mitochondrion, chloroplast thylakoid membrane, plastid; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41 (InterPro:IPR000642), Peptidase M41, FtsH extracellular (InterPro:IPR011546); BEST Arabidopsis thaliana protein match is: FTSH protease 3 (TAIR:AT2G29080.1); Has 37747 Blast hits to 35440 proteins in 3262 species: Archae - 1533; Bacteria - 14237; Metazoa - 4767; Fungi - 3643; Plants - 3223; Viruses - 27; Other Eukaryotes - 10317 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2304435..2312399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100625.4 → NP_172231.2  FTSH protease 10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172231.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WLM5, Q8VZI8, Q9LNX5
      UniProtKB/TrEMBL
      A0A178WKK3, A0A5S9T4Q8
      Conserved Domains (5) summary
      TIGR01241
      Location:263 → 762
      FtsH_fam; ATP-dependent metalloprotease FtsH
      pfam00004
      Location:364 → 496
      AAA; ATPase family associated with various cellular activities (AAA)
      pfam01434
      Location:579 → 760
      Peptidase_M41; Peptidase family M41
      pfam06480
      Location:139 → 254
      FtsH_ext; FtsH Extracellular
      cl21455
      Location:311 → 414
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VZI8.1

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