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    Ptar1 protein prenyltransferase alpha subunit repeat containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 72351, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ptar1provided by MGI
    Official Full Name
    protein prenyltransferase alpha subunit repeat containing 1provided by MGI
    Primary source
    MGI:MGI:1921875
    See related
    Ensembl:ENSMUSG00000074925 AllianceGenome:MGI:1921875
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700084D09Rik; 2010013L17Rik; 4930428J16Rik
    Summary
    Predicted to be involved in protein prenylation. Predicted to be active in cytoplasm. Orthologous to human PTAR1 (protein prenyltransferase alpha subunit repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 3.1), CNS E11.5 (RPKM 2.3) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ptar1 in Genome Data Viewer
    Location:
    19 B; 19 18.45 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (23664728..23710249)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (23687361..23732885)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 95 Neighboring gene STARR-seq mESC enhancer starr_45778 Neighboring gene predicted gene, 22144 Neighboring gene SAP domain containing ribonucleoprotein pseudogene Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene predicted gene, 34076 Neighboring gene STARR-seq mESC enhancer starr_45783 Neighboring gene endosomal transmembrane epsin interactor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of Modifier Genes in a Mouse Model of Gaucher Disease. Klein AD, et al. Cell Rep, 2016 Sep 6. PMID 27568557
    2. Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA. Scavuzzo MA, et al. Cell Rep, 2018 Dec 26. PMID 30590051
    3. Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. Lawson KA, et al. Nature, 2020 Oct. PMID 32968282, Free PMC Article
    4. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in protein prenylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein prenyltransferase alpha subunit repeat-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028208.1 → NP_082484.1  protein prenyltransferase alpha subunit repeat-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      AC132088, AC134830
      Consensus CDS
      CCDS50405.1
      UniProtKB/TrEMBL
      A0A494B9V8
      Related
      ENSMUSP00000157782.2, ENSMUST00000237333.2
      Conserved Domains (2) summary
      PLN02789
      Location:89 → 315
      PLN02789; farnesyltranstransferase
      pfam01239
      Location:180 → 207
      PPTA; Protein prenyltransferase alpha subunit repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      23664728..23710249
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527361.5 → XP_006527424.1  protein prenyltransferase alpha subunit repeat-containing protein 1 isoform X1

      Conserved Domains (1) summary
      PLN02789
      Location:89 → 315
      PLN02789; farnesyltranstransferase
    Nucleotide Protein Strain
    Heading Accession and Version

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