Clec14a C-type lectin domain containing 14A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Clec14aprovided by RGD
Official Full Name: C-type lectin domain containing 14Aprovided by RGD
Primary source: RGD:1306232
See related: Ensembl:ENSRNOG00000022697 AllianceGenome:RGD:1306232
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1306232
Summary: Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Predicted to be involved in cell migration involved in sprouting angiogenesis. Predicted to act upstream of or within with a positive effect on vascular endothelial growth factor receptor-3 signaling pathway. Predicted to act upstream of or within with a negative effect on vascular endothelial growth factor receptor-2 signaling pathway. Predicted to act upstream of or within lymphangiogenesis and sprouting angiogenesis. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC14A (C-type lectin domain containing 14A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: 6q23

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (81616414..81619556, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (75881470..75884612, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (79303301..79306443, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables extracellular matrix binding	IBA Inferred from Biological aspect of Ancestor more info
enables extracellular matrix protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables extracellular matrix protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cell migration	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell migration involved in sprouting angiogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within lymphangiogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within sprouting angiogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within_negative_effect vascular endothelial growth factor receptor-2 signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in vascular endothelial growth factor receptor-2 signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within_positive_effect vascular endothelial growth factor receptor-3 signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in vascular endothelial growth factor receptor-3 signaling pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in external side of plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: C-type lectin domain family 14 member A

Names: C-type lectin domain family 14, member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.