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    P2ry10 P2Y receptor family member 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317219, updated on 11-Apr-2024

    Summary

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    Official Symbol
    P2ry10provided by RGD
    Official Full Name
    P2Y receptor family member 10provided by RGD
    Primary source
    RGD:1561912
    See related
    Ensembl:ENSRNOG00000037839 AllianceGenome:RGD:1561912
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561912
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to be integral component of plasma membrane. Orthologous to human P2RY10 (P2Y receptor family member 10). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 331.0), Spleen (RPKM 175.8) and 1 other tissue See more
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    Genomic context

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    See P2ry10 in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (76184064..76279996)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (72121558..72207174)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (78158729..78210413)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene lysophosphatidic acid receptor 4 Neighboring gene U6 spliceosomal RNA Neighboring gene P2Y receptor family member 10B Neighboring gene prohibitin 1, pseudogene 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Clone Names

    • MGC189289

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    putative P2Y purinoceptor 10
    Names
    purinergic receptor P2Y, G-protein coupled, 10
    purinergic receptor P2Y10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177682.1 → NP_001171153.1  putative P2Y purinoceptor 10

      See identical proteins and their annotated locations for NP_001171153.1

      Status: PROVISIONAL

      Source sequence(s)
      BC168967
      UniProtKB/TrEMBL
      A6IV61, B5DF87
      Related
      ENSRNOP00000046594.3, ENSRNOT00000048695.6
      Conserved Domains (2) summary
      cd14964
      Location:23 → 50
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:23 → 305
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      76184064..76279996
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063280020.1 → XP_063136090.1  putative P2Y purinoceptor 10 isoform X1

    2. XM_039099736.2 → XP_038955664.1  putative P2Y purinoceptor 10 isoform X2

      UniProtKB/TrEMBL
      A6IV61, B5DF87
      Related
      ENSRNOP00000092809.1
      Conserved Domains (2) summary
      cd14964
      Location:23 → 50
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:23 → 305
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_063280021.1 → XP_063136091.1  putative P2Y purinoceptor 10 isoform X2

      UniProtKB/TrEMBL
      B5DF87

    4. XM_039099737.2 → XP_038955665.1  putative P2Y purinoceptor 10 isoform X2

      UniProtKB/TrEMBL
      A6IV61, B5DF87
      Conserved Domains (2) summary
      cd14964
      Location:23 → 50
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:23 → 305
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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