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    ROPGEF10 ROP uanine nucleotide exchange factor 10 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832076, updated on 15-Feb-2024

    Summary

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    Gene symbol
    ROPGEF10
    Gene description
    ROP uanine nucleotide exchange factor 10
    Primary source
    Araport:AT5G19560
    Locus tag
    AT5G19560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA ROP UANINE NUCLEOTIDE EXCHANGE FACTOR 10; ATROPGEF10; GEF10; guanine exchange factor 10; ROP (rho of plants) guanine nucleotide exchange factor 10; ROP uanine nucleotide exchange factor 10; T20D1.80; T20D1_80
    Summary
    Encodes a member of KPP-like gene family, homolog of KPP (kinase partner protein) gene in tomato. Also a member of the RopGEF (guanine nucleotide exchange factor) family, containing the novel PRONE domain (plant-specific Rop nucleotide exchanger), which is exclusively active towards members of the Rop subfamily.
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    Genomic context

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    See ROPGEF10 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (6602910..6606506)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene thermosome subunit gamma Neighboring gene aspartate aminotransferase 2 Neighboring gene uncharacterized protein Neighboring gene glyoxal oxidase-related protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis RopGEF4 and RopGEF10 are important for FERONIA-mediated developmental but not environmental regulation of root hair growth. Huang GQ, et al. New Phytol, 2013 Dec. PMID 23915272
    2. FERONIA receptor kinase pathway suppresses abscisic acid signaling in Arabidopsis by activating ABI2 phosphatase. Yu F, et al. Proc Natl Acad Sci U S A, 2012 Sep 4. PMID 22908257, Free PMC Article
    3. Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Gu Y, et al. Plant Cell, 2006 Feb. PMID 16415208, Free PMC Article
    4. A new family of RhoGEFs activates the Rop molecular switch in plants. Berken A, et al. Nature, 2005 Aug 25. PMID 15980860
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RopGEF4 and RopGEF10 are genetic components in FER-mediated, developmentally (but not environmentally) regulated, root hair growth.
      Title: Arabidopsis RopGEF4 and RopGEF10 are important for FERONIA-mediated developmental but not environmental regulation of root hair growth.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001343611.1
    NM_121961.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ROP uanine nucleotide exchange factor 10
    NP_001318601.1
    • ROP uanine nucleotide exchange factor 10 (ROPGEF10); CONTAINS InterPro DOMAIN/s: Rop nucleotide exchanger, PRONE (InterPro:IPR005512); BEST Arabidopsis thaliana protein match is: RHO guanyl-nucleotide exchange factor 8 (TAIR:AT3G24620.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6602910..6606506
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343613.1 → NP_001331395.1  ROP uanine nucleotide exchange factor 10 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BDP4

    2. NM_001343612.1 → NP_001331396.1  ROP uanine nucleotide exchange factor 10 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BDS2

    3. NM_001343614.1 → NP_001331397.1  ROP uanine nucleotide exchange factor 10 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BDV2, A0A7G2F9V8
      Conserved Domains (1) summary
      pfam03759
      Location:62 → 415
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)

    4. NM_001343611.1 → NP_001318601.1  ROP uanine nucleotide exchange factor 10 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MFH1, Q1KS66
      UniProtKB/TrEMBL
      A0A178U9P8, A0A5S9Y5L8, A0A7G2F9V8
      Conserved Domains (1) summary
      pfam03759
      Location:43 → 396
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)

    5. NM_121961.2 → NP_197457.1  ROP uanine nucleotide exchange factor 10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197457.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MFH1, Q1KS66
      UniProtKB/TrEMBL
      A0A178U9P8, A0A5S9Y5L8, A0A7G2F9V8
      Conserved Domains (1) summary
      pfam03759
      Location:43 → 396
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1KS66.1

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