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    Capsl calcyphosine-like [ Mus musculus (house mouse) ]

    Gene ID: 75568, updated on 12-May-2024

    Summary

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    Official Symbol
    Capslprovided by MGI
    Official Full Name
    calcyphosine-likeprovided by MGI
    Primary source
    MGI:MGI:1922818
    See related
    Ensembl:ENSMUSG00000039676 AllianceGenome:MGI:1922818
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700028N11Rik
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be located in cytoplasm. Is expressed in several structures, including brain ventricle and choroid plexus; extraembryonic ectoderm; nasal cavity epithelium; pancreas epithelium; and primitive streak. Orthologous to human CAPSL (calcyphosine like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 3.0), bladder adult (RPKM 2.2) and 18 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Capsl in Genome Data Viewer
    Location:
    15 A1; 15 4.09 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (9436136..9466125)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (9436016..9466039)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_37936 Neighboring gene UDP glycosyltransferases 3 family, polypeptide A2 Neighboring gene STARR-seq mESC enhancer starr_37937 Neighboring gene STARR-seq mESC enhancer starr_37938 Neighboring gene STARR-seq mESC enhancer starr_37939 Neighboring gene UDP glycosyltransferases 3 family, polypeptide A1 pseudogene Neighboring gene interleukin 7 receptor Neighboring gene sperm flagellar 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice. Michaud EJ, et al. BMC Genomics, 2005 Nov 21. PMID 16300676, Free PMC Article
    2. Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection. Sousa-Nunes R, et al. Genome Res, 2003 Dec. PMID 14613977, Free PMC Article
    3. A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis. Jones MR, et al. Front Genet, 2018. PMID 30728831, Free PMC Article
    4. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
    5. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (2)  1 citation
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC74120

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    calcyphosin-like protein
    Names
    Calcyphosine

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418759.1 → NP_001405688.1  calcyphosin-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC162301
      UniProtKB/TrEMBL
      A0A2I3BPX5
      Related
      ENSMUSP00000153958.2, ENSMUST00000226688.2

    2. NM_029341.2 → NP_083617.2  calcyphosin-like protein isoform 1

      See identical proteins and their annotated locations for NP_083617.2

      Status: VALIDATED

      Source sequence(s)
      AC162301
      Consensus CDS
      CCDS37040.1
      UniProtKB/Swiss-Prot
      Q5U5X2, Q6P8Y1, Q9D9U6
      Related
      ENSMUSP00000035663.4, ENSMUST00000042360.5
      Conserved Domains (3) summary
      cd00051
      Location:46 → 101
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:80 → 140
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:116 → 182
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      9436136..9466125
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520185.2 → XP_006520248.1  calcyphosin-like protein isoform X1

      Conserved Domains (1) summary
      pfam13499
      Location:65 → 137
      EF-hand_7; EF-hand domain pair
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P8Y1.4 GenPept UniProtKB/Swiss-Prot:Q6P8Y1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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