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    Or2v1 olfactory receptor family 2 subfamily V member 1 [ Mus musculus (house mouse) ]

    Gene ID: 18356, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Or2v1provided by MGI
    Official Full Name
    olfactory receptor family 2 subfamily V member 1provided by MGI
    Primary source
    MGI:MGI:1333785
    See related
    Ensembl:ENSMUSG00000040328 AllianceGenome:MGI:1333785
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    IF7; Olfr56; MOR276-1
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Or2v1 in Genome Data Viewer
    Location:
    11 B1.2; 11 29.05 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (49025000..49026214)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (49134173..49135387)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51892 Neighboring gene olfactory receptor family 2 subfamily V member 2 Neighboring gene STARR-seq mESC enhancer starr_29369 Neighboring gene olfactory receptor family 2 subfamily T member 26 Neighboring gene STARR-seq mESC enhancer starr_29370 Neighboring gene olfactory receptor family 2 subfamily O member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of ligands for olfactory receptors by functional expression of a receptor library. Krautwurst D, et al. Cell, 1998 Dec 23. PMID 9875846
    2. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    3. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    4. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
    5. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within response to stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 2V1
    Names
    GA_x6K02T2QP88-6300500-6299553
    olfactory receptor 276-1
    olfactory receptor 56
    olfactory receptor F7
    olfactory receptor G3
    olfactory receptor I-G7
    olfactory receptor MOR276-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010999.3 → NP_035129.2  olfactory receptor 2V1

      Status: VALIDATED

      Source sequence(s)
      AL645688
      Consensus CDS
      CCDS24597.2
      UniProtKB/Swiss-Prot
      Q8BKF2, Q8VGD6, Q9QUL1, Q9Z1U2
      Related
      ENSMUSP00000158965.2, ENSMUST00000238881.2
      Conserved Domains (1) summary
      cd15421
      Location:26 → 302
      7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      49025000..49026214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VGD6.1 GenPept UniProtKB/Swiss-Prot:Q8VGD6

    Gene LinkOut

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