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    AU018091 expressed sequence AU018091 [ Mus musculus (house mouse) ]

    Gene ID: 245128, updated on 11-Apr-2024

    Summary

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    Official Symbol
    AU018091provided by MGI
    Official Full Name
    expressed sequence AU018091provided by MGI
    Primary source
    MGI:MGI:2142124
    See related
    Ensembl:ENSMUSG00000054753 AllianceGenome:MGI:2142124
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    cat-5
    Summary
    Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in placenta adult (RPKM 6.6) and testis adult (RPKM 1.5) See more
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    Genomic context

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    See AU018091 in Genome Data Viewer
    Location:
    7 A1; 7 1.84 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (3204498..3219029, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (3154658..3169203, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated glutamate (E)-rich protein 9, pseudogene 1 Neighboring gene zinc finger pseudogene Neighboring gene proteasome subunit beta type 5 precursor (proteasome epsilon chain) (Macropain epsilon chain) (multicatalytic endopeptidase complex epsilon chain) (proteasome subunit X) (proteasome chain 6) Neighboring gene STARR-seq mESC enhancer starr_17882 Neighboring gene CRISPRi-validated Mir290 enhancer cluster Neighboring gene microRNA 290a Neighboring gene microRNA 290b Neighboring gene NLR family, pyrin domain containing 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC91100, MGC91107

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables L-arginine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-lysine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-ornithine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-arginine import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-ornithine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cationic amino acid transporter 5
    Names
    cationic amino acid transporter member 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004153.2 → NP_001004153.2  cationic amino acid transporter 5

      Status: VALIDATED

      Source sequence(s)
      AB201954, BC080735
      Consensus CDS
      CCDS39724.2
      UniProtKB/TrEMBL
      E9PWS4, Q0PDJ1
      Related
      ENSMUSP00000126800.2, ENSMUST00000171749.3
      Conserved Domains (2) summary
      TIGR00906
      Location:53 → 656
      2A0303; cationic amino acid transport permease
      pfam13906
      Location:604 → 654
      AA_permease_C; C-terminus of AA_permease

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      3204498..3219029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539984.3 → XP_006540047.1  cationic amino acid transporter 5 isoform X1

      See identical proteins and their annotated locations for XP_006540047.1

      UniProtKB/TrEMBL
      Q0PDJ1
      Related
      ENSMUST00000205185.2
      Conserved Domains (1) summary
      TIGR00906
      Location:52 → 655
      2A0303; cationic amino acid transport permease
    Nucleotide Protein Strain
    Heading Accession and Version

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