St6galnac5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: St6galnac5provided by MGI
Official Full Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5provided by MGI
Primary source: MGI:MGI:1349471
See related: Ensembl:ENSMUSG00000039037 AllianceGenome:MGI:1349471
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Siat7e
Summary: Enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Involved in glycosphingolipid biosynthetic process and oligosaccharide biosynthetic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and respiratory system. Orthologous to human ST6GALNAC5 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in CNS E18 (RPKM 13.8), frontal lobe adult (RPKM 11.3) and 13 other tissues See more
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 3 H3; 3 77.16 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (152525522..152687847, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (152819885..152982210, complement)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

AI851940 (e-PCR)
- UniSTS:178956

D3Mit322 (e-PCR), detects polymorphism
- UniSTS:129760

18.MMHAP61FRF9.seq (e-PCR)
- UniSTS:123390

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables sialyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ganglioside biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in glycosphingolipid biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in oligosaccharide biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in oligosaccharide metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5

Names: GD1 alpha synthase; SIAT7-E; ST6GalNAc V; ST6GalNAcV; galNAc alpha-2,6-sialyltransferase V; sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) E; sialyltransferase 7E

NP_036158.3

EC 2.4.3.3

EC 2.4.99.-

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.