U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Slc39a1 solute carrier family 39 member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361986, updated on 27-Mar-2024

    Summary

    Official Symbol
    Slc39a1provided by RGD
    Official Full Name
    solute carrier family 39 member 1provided by RGD
    Primary source
    RGD:1305241
    See related
    Ensembl:ENSRNOG00000059463 AllianceGenome:RGD:1305241
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables signaling receptor binding activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to act upstream of or within chordate embryonic development; limb development; and zinc ion transport. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human SLC39A1 (solute carrier family 39 member 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 537.2), Liver (RPKM 480.1) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Slc39a1 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (178001052..178006689)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (175703413..175709063)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (189609766..189615367)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene jumping translocation breakpoint Neighboring gene cAMP responsive element binding protein 3-like 4 Neighboring gene CREB regulated transcription coactivator 2 Neighboring gene DENN domain containing 4B Neighboring gene uncharacterized LOC102551157

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables zinc ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryonic cranial skeleton morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within limb development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in zinc ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in zinc ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within zinc ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc transporter ZIP1
    Names
    solute carrier family 39 (zinc transporter), member 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134577.3NP_001128049.1  zinc transporter ZIP1

      See identical proteins and their annotated locations for NP_001128049.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      B5DEF5
      Conserved Domains (1) summary
      pfam02535
      Location:48319
      Zip; ZIP Zinc transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      178001052..178006689
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006232707.4XP_006232769.1  zinc transporter ZIP1 isoform X1

      See identical proteins and their annotated locations for XP_006232769.1

      UniProtKB/TrEMBL
      B5DEF5
      Related
      ENSRNOP00000071120.1
      Conserved Domains (1) summary
      pfam02535
      Location:48319
      Zip; ZIP Zinc transporter