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    Kif6 kinesin family member 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171291, updated on 11-Apr-2024

    Summary

    Official Symbol
    Kif6provided by RGD
    Official Full Name
    kinesin family member 6provided by RGD
    Primary source
    RGD:621070
    See related
    Ensembl:ENSRNOG00000011453 AllianceGenome:RGD:621070
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Krp3
    Summary
    Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Located in male germ cell nucleus. Orthologous to human KIF6 (kinesin family member 6). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 20.2), Lung (RPKM 17.9) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Kif6 in Genome Data Viewer
    Location:
    9q12
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (18573925..18870789, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (11076203..11373205, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (13016973..13311971, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480333 Neighboring gene potassium two pore domain channel subfamily K member 16, pseudogene 1 Neighboring gene uncharacterized LOC134480334 Neighboring gene dishevelled associated activator of morphogenesis 2 Neighboring gene uncharacterized LOC134480336 Neighboring gene molybdenum cofactor synthesis 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spermatogenesis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of kinesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in male germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    kinesin-like protein KIF6
    Names
    kinesin-related protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      18573925..18870789 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244480.4XP_006244542.1  kinesin-like protein KIF6

      See identical proteins and their annotated locations for XP_006244542.1

      UniProtKB/TrEMBL
      E9PSL8
      Related
      ENSRNOP00000015584.8
      Conserved Domains (2) summary
      cd01375
      Location:5343
      KISc_KIF9_like; Kinesin motor domain, KIF9-like subgroup
      pfam00225
      Location:28345
      Kinesin; Kinesin motor domain