Scgb2a1 secretoglobin, family 2A, member 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Scgb2a1provided by RGD
Full Name: secretoglobin, family 2A, member 1provided by RGD
Primary source: RGD:735031
See related: Ensembl:ENSRNOG00000023151 AllianceGenome:RGD:735031
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: C3.1; Psbp1; Psbpc3; Scgb2a2
Summary: Predicted to enable steroid binding activity. Predicted to be involved in androgen receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human SCGB2A1 (secretoglobin family 2A member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Thymus (RPKM 6.9), Brain (RPKM 3.0) and 7 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1q43

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (215922751..215926114)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (206497848..206501211)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (225899313..225902676)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BI278940 (e-PCR)
- UniSTS:244484

BI283066 (e-PCR)
- UniSTS:243463

BI278974 (e-PCR)
- UniSTS:244487

D1Wox54 (e-PCR)
- UniSTS:518687

RH144324 (e-PCR)
- UniSTS:233569

D1Wox44 (e-PCR)
- UniSTS:239554

D1Arb39 (e-PCR), detects polymorphism
- UniSTS:227013

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein-containing complex binding	TAS Traceable Author Statement more info	PubMed
enables steroid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in androgen receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in androgen receptor signaling pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
located_in extracellular space	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: secretoglobin family 2A member 2

Names: androgen receptor DNA-binding domain DNA; prostatein C3 subunit; prostatein peptide C3; prostatic steroid-binding protein 1; prostatic steroid-binding protein C3; prostatic steroid-binding protein C3.2; secretoglobin, family 2A, member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_203333.2 → NP_976078.1 secretoglobin family 2A member 2 precursor

See identical proteins and their annotated locations for NP_976078.1

Status: VALIDATED

Source sequence(s)

BC062401, CB791758, JAXUCZ010000001

UniProtKB/Swiss-Prot

P02780, Q63463, Q9JHB9

UniProtKB/TrEMBL

A6HZZ8

Related

ENSRNOP00000037869.2, ENSRNOT00000031612.4

Conserved Domains (1) summary

pfam01099
Location:1 → 91

Uteroglobin; Uteroglobin family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

215922751..215926114

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_080770.3: Suppressed sequence

Description

NM_080770.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.