Galm galactose mutarotase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Galmprovided by RGD
Official Full Name: galactose mutarotaseprovided by RGD
Primary source: RGD:1359459
See related: Ensembl:ENSRNOG00000007023 AllianceGenome:RGD:1359459
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable aldose 1-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose and glucose metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in galactosemia. Orthologous to human GALM (galactose mutarotase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 703.9), Liver (RPKM 280.8) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 6q12

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (20589775..20641516, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (14837540..14889484, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (2808988..2860742)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH129850 (e-PCR)
- UniSTS:213138

AA892666 (e-PCR)
- UniSTS:261539

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables aldose 1-epimerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables aldose 1-epimerase activity	IEA Inferred from Electronic Annotation more info
enables aldose 1-epimerase activity	ISO Inferred from Sequence Orthology more info
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info
NOT enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	ISO Inferred from Sequence Orthology more info
involved_in galactose catabolic process via UDP-galactose	IBA Inferred from Biological aspect of Ancestor more info
involved_in galactose catabolic process via UDP-galactose	IEA Inferred from Electronic Annotation more info
involved_in galactose catabolic process via UDP-galactose	ISO Inferred from Sequence Orthology more info
involved_in galactose metabolic process	ISO Inferred from Sequence Orthology more info
involved_in glucose metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in glucose metabolic process	IEA Inferred from Electronic Annotation more info
involved_in glucose metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: galactose mutarotase

Names: aldose 1-epimerase

NP_001007705.1

EC 5.1.3.3

XP_063117896.1

EC 5.1.3.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.