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    CG17270 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42462, updated on 10-May-2024

    Summary

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    Official Symbol
    CG17270provided by FlyBase
    Primary source
    FLYBASE:FBgn0038828
    Locus tag
    Dmel_CG17270
    See related
    AllianceGenome:FB:FBgn0038828
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-Liu; Dmel\CG17270
    Summary
    Predicted to enable protein-macromolecule adaptor activity. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in adult head and organism. Orthologous to human ERG28 (ergosterol biosynthesis 28 homolog). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG17270 in Genome Data Viewer
    Location:
    93A1-93A1; 3-69 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20816445..20818929, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16642167..16644651, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Syncrip Neighboring gene Tak1-like 1 Neighboring gene Fancd2 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein S20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. Vinci G, et al. PLoS One, 2008 Aug 6. PMID 18682733, Free PMC Article
    2. Genome-wide analysis of Staufen-associated mRNAs identifies secondary structures that confer target specificity. Laver JD, et al. Nucleic Acids Res, 2013 Nov. PMID 23945942, Free PMC Article
    3. A single-cell atlas reveals unanticipated cell type complexity in Drosophila ovaries. Slaidina M, et al. Genome Res, 2021 Oct. PMID 34389661, Free PMC Article
    4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17270-PA
    CG17270-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      20816445..20818929 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142658.3 → NP_650915.1  uncharacterized protein Dmel_CG17270, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650915.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ST95, Q9VDI6
      Related
      FBpp0083398
      Conserved Domains (1) summary
      pfam03694
      Location:16 → 125
      Erg28; Erg28 like protein

    2. NM_001275856.1 → NP_001262785.1  uncharacterized protein Dmel_CG17270, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262785.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ST95, Q9VDI6
      Conserved Domains (1) summary
      pfam03694
      Location:16 → 125
      Erg28; Erg28 like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VDI6 Q9VDI6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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