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    CG15553 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43677, updated on 10-May-2024

    Summary

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    Official Symbol
    CG15553provided by FlyBase
    Primary source
    FLYBASE:FBgn0039817
    Locus tag
    Dmel_CG15553
    See related
    AllianceGenome:FB:FBgn0039817
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15553
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in hereditary folate malabsorption. Orthologous to human SLC46A1 (solute carrier family 46 member 1) and SLC46A3 (solute carrier family 46 member 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG15553 in Genome Data Viewer
    Location:
    100B2-100B2; 3-102 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31098868..31101169, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26924590..26926891, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Sox100B Neighboring gene uncharacterized protein Neighboring gene mayo Neighboring gene Proteasome alpha3 subunit, Testis-specific

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Validation of Candidate Genes Detected by Genomic Feature Models. Rohde PD, et al. G3 (Bethesda), 2018 May 4. PMID 29519937, Free PMC Article
    2. SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans. Paik D, et al. J Immunol, 2017 Jul 1. PMID 28539433, Free PMC Article
    3. The Drosophila Tis11 protein and its effects on mRNA expression in flies. Choi YJ, et al. J Biol Chem, 2014 Dec 19. PMID 25342740, Free PMC Article
    4. Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila. Lamiable O, et al. Proc Natl Acad Sci U S A, 2016 Jan 19. PMID 26739560, Free PMC Article
    5. A Glio-Protective Role of mir-263a by Tuning Sensitivity to Glutamate. Aw SS, et al. Cell Rep, 2017 May 30. PMID 28564598

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15553-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31098868..31101169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143584.4 → NP_651841.3  uncharacterized protein Dmel_CG15553 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651841.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VA14
      Conserved Domains (2) summary
      pfam07690
      Location:96 → 469
      MFS_1; Major Facilitator Superfamily
      cl21472
      Location:97 → 239
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VA14 Q9VA14

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