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    NUC C2H2-like zinc finger protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834439, updated on 7-Sep-2023

    Summary

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    Gene symbol
    NUC
    Gene description
    C2H2-like zinc finger protein
    Primary source
    Araport:AT5G44160
    Locus tag
    AT5G44160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtIDD8; IDD8; INDETERMINATE DOMAIN 8; MLN1.8; MLN1_8; nutcracker
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    Genomic context

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    See NUC in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (17772856..17775749)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene FASCICLIN-like arabinogalactan protein 13 precursor Neighboring gene phosphorelay protein Neighboring gene prohibitin 7 Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene Homeodomain-like transcriptional regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Modulation of sugar metabolism by an INDETERMINATE DOMAIN transcription factor contributes to photoperiodic flowering in Arabidopsis. Seo PJ, et al. Plant J, 2011 Feb. PMID 21265895
    2. AKIN10 delays flowering by inactivating IDD8 transcription factor through protein phosphorylation in Arabidopsis. Jeong EY, et al. BMC Plant Biol, 2015 May 1. PMID 25929516, Free PMC Article
    3. In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots. Long Y, et al. Nature, 2017 Aug 3. PMID 28746306
    4. Arabidopsis BIRD Zinc Finger Proteins Jointly Stabilize Tissue Boundaries by Confining the Cell Fate Regulator SHORT-ROOT and Contributing to Fate Specification. Long Y, et al. Plant Cell, 2015 Apr. PMID 25829440, Free PMC Article
    5. Transcriptional control of tissue formation throughout root development. Moreno-Risueno MA, et al. Science, 2015 Oct 23. PMID 26494755, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_123783.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within asymmetric cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within photoperiodism, flowering IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein localization to nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of meristem growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of timing of transition from vegetative to reproductive phase IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of timing of transition from vegetative to reproductive phase IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    C2H2-like zinc finger protein
    NP_199229.1
    • nutcracker (NUC); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity, zinc ion binding, nucleic acid binding; INVOLVED IN: regulation of transcription; LOCATED IN: intracellular; EXPRESSED IN: primary root apical meristem, stem vascular system, embryo, root, embryonic root; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, C2H2-type (InterPro:IPR007087); BEST Arabidopsis thaliana protein match is: C2H2 and C2HC zinc fingers superfamily protein (TAIR:AT1G03840.1); Has 52823 Blast hits to 19358 proteins in 362 species: Archae - 0; Bacteria - 0; Metazoa - 50211; Fungi - 300; Plants - 764; Viruses - 0; Other Eukaryotes - 1548 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17772856..17775749
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344535.1 → NP_001330762.1  C2H2-like zinc finger protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBS4, A0A7G2FKB0

    2. NM_123783.4 → NP_199229.1  C2H2-like zinc finger protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199229.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FFH3
      UniProtKB/TrEMBL
      A0A654G8B9, A0A7G2FKB0
      Conserved Domains (1) summary
      sd00017
      Location:68 → 88
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FFH3.1

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