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    BGLAP bone gamma-carboxyglutamate protein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718296, updated on 5-Mar-2024

    Summary

    Gene symbol
    BGLAP
    Gene description
    bone gamma-carboxyglutamate protein
    Locus tag
    EGK_01412
    See related
    Ensembl:ENSMMUG00000004902
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See BGLAP in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (94726028..94726954, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (130854445..130855371)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene SMG5 nonsense mediated mRNA decay factor Neighboring gene progestin and adipoQ receptor family member 6 Neighboring gene polyamine-modulated factor 1 Neighboring gene solute carrier family 25 member 44 Neighboring gene uncharacterized LOC106992879

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables hydroxyapatite binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables structural constituent of bone IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in bone development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in osteoblast differentiation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of bone mineralization IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of cellular response to insulin stimulus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in response to vitamin K IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    osteocalcin
    Names
    BGP
    bone Gla protein
    bone gamma-carboxyglutamate (gla) protein (osteocalcin)
    gamma-carboxyglutamic acid-containing protein
    osteocalcin preproprotein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080768.1NP_001074237.1  osteocalcin precursor

      See identical proteins and their annotated locations for NP_001074237.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ976876
      UniProtKB/Swiss-Prot
      A2D670
      UniProtKB/TrEMBL
      A0A1D5QKK7, A0A8J8Y2R9, G7MDZ1, H9EX61
      Related
      ENSMMUP00000000113.2, ENSMMUT00000000124.4
      Conserved Domains (1) summary
      smart00069
      Location:3397
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      94726028..94726954 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)