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    CG10053 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40871, updated on 10-May-2024

    Summary

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    Official Symbol
    CG10053provided by FlyBase
    Primary source
    FLYBASE:FBgn0037490
    Locus tag
    Dmel_CG10053
    See related
    AllianceGenome:FB:FBgn0037490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:LD41878; BEST:LD45537; Dmel\CG10053
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to be active in kinetochore. Is expressed in several structures, including anterior endoderm anlage; embryonic/larval midgut primordium; esophageal visceral muscle; germ layer; and visceral muscle primordium. Orthologous to human GPATCH11 (G-patch domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG10053 in Genome Data Viewer
    Location:
    84D3-84D3; 3-48 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (7247090..7248140)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (3072812..3073862)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Nucleolar complex protein 3 Neighboring gene uncharacterized protein Neighboring gene DTW domain containing 2 Neighboring gene Odorant-binding protein 84a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic variants regulating expression levels and isoform diversity during embryogenesis. Cannavò E, et al. Nature, 2017 Jan 19. PMID 28024300
    2. Identification of genes involved in the same pathways using a Hidden Markov Model-based approach. Senf A, et al. Bioinformatics, 2009 Nov 15. PMID 19720676
    3. RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins. Lu Z, et al. Genome Biol, 2014 Jan 7. PMID 24393626, Free PMC Article
    4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10053-PA
    CG10053-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      7247090..7248140
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300277.1 → NP_001287206.1  uncharacterized protein Dmel_CG10053, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287206.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RB3, Q9VI83
      Conserved Domains (2) summary
      pfam01585
      Location:73 → 116
      G-patch; G-patch domain
      pfam13821
      Location:219 → 266
      DUF4187; Domain of unknown function (DUF4187)

    2. NM_141454.3 → NP_649711.1  uncharacterized protein Dmel_CG10053, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649711.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RB3, Q9VI83
      Related
      FBpp0081095
      Conserved Domains (2) summary
      pfam01585
      Location:73 → 116
      G-patch; G-patch domain
      pfam13821
      Location:219 → 266
      DUF4187; Domain of unknown function (DUF4187)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VI83 Q9VI83

    Gene LinkOut

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