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    CG4291 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33264, updated on 10-May-2024

    Summary

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    Official Symbol
    CG4291provided by FlyBase
    Primary source
    FLYBASE:FBgn0031287
    Locus tag
    Dmel_CG4291
    See related
    AllianceGenome:FB:FBgn0031287
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4291
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of precatalytic spliceosome. Orthologous to human WBP4 (WW domain binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG4291 in Genome Data Viewer
    Location:
    21E2-21E2; 2-1.5 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (851251..852730, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (851251..852730, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene dreadlocks Neighboring gene drongo Neighboring gene long non-coding RNA:CR44060 Neighboring gene kraken Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of hunger-driven gene expression in the Drosophila melanogaster larval central nervous system. Ryuda M, et al. Zoolog Sci, 2008 Jul. PMID 18828662
    2. Microarray analysis of replicate populations selected against a wing-shape correlation in Drosophila melanogaster. Weber KE, et al. Genetics, 2008 Feb. PMID 18245369, Free PMC Article
    3. Pre-messenger RNA processing factors in the Drosophila genome. Mount SM, et al. J Cell Biol, 2000 Jul 24. PMID 10908584, Free PMC Article
    4. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222, Free PMC Article
    5. Nociceptor-Enriched Genes Required for Normal Thermal Nociception. Honjo K, et al. Cell Rep, 2016 Jul 12. PMID 27346357, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of precatalytic spliceosome HDA PubMed 
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small nuclear ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4291-PA
    CG4291-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      851251..852730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272917.1 → NP_001259846.1  uncharacterized protein Dmel_CG4291, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259846.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NNF4, Q9VPU4
      Conserved Domains (2) summary
      cl22907
      Location:10 → 44
      zf-U1; U1 zinc finger
      pfam00397
      Location:152 → 177
      WW; WW domain

    2. NM_134707.3 → NP_608551.1  uncharacterized protein Dmel_CG4291, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608551.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NNF4, Q9VPU4
      Related
      FBpp0077698
      Conserved Domains (2) summary
      cl22907
      Location:10 → 44
      zf-U1; U1 zinc finger
      pfam00397
      Location:152 → 177
      WW; WW domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MRL9 Q8MRL9
    Q9VPU4 Q9VPU4

    Gene LinkOut

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