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    TotC Turandot C [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 117462, updated on 10-May-2024

    Summary

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    Official Symbol
    TotCprovided by FlyBase
    Official Full Name
    Turandot Cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0044812
    Locus tag
    Dmel_CG31508
    See related
    AllianceGenome:FB:FBgn0044812
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31508; Dmel\CG31508; tot; totC; TOTc
    Summary
    Involved in several processes, including cellular response to UV; cellular response to heat; and response to bacterium. Predicted to be located in extracellular space. Is expressed in adult head. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See TotC in Genome Data Viewer
    Location:
    93A2-93A2; 3-69 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20872988..20873580)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16698710..16699302)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Kainate-type ionotropic glutamate receptor subunit 1D Neighboring gene Turandot A Neighboring gene Turandot B Neighboring gene Turandot Z

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Immune anticipation of mating in Drosophila: Turandot M promotes immunity against sexually transmitted fungal infections. Zhong W, et al. Proc Biol Sci, 2013 Dec 22. PMID 24174107, Free PMC Article
    2. Parallel gene expression evolution in natural and laboratory evolved populations. Hsu SK, et al. Mol Ecol, 2021 Feb. PMID 32979867, Free PMC Article
    3. Hormesis results in trade-offs with immunity. McClure CD, et al. Evolution, 2014 Aug. PMID 24862588, Free PMC Article
    4. A functional study of the role of Turandot genes in Drosophila melanogaster: An emerging candidate mechanism for inducible heat tolerance. Amstrup AB, et al. J Insect Physiol, 2022 Nov-Dec. PMID 36396076
    5. Circadian regulation of the Drosophila astrocyte transcriptome. You S, et al. PLoS Genet, 2021 Sep. PMID 34543266, Free PMC Article

    See all (97) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cellular response to UV IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to UV IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to heat IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to oxidative stress IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    turandot C
    Names
    CG31508-PA
    Stress-inducible humoral factor turandot C
    TotC-PA
    turandot

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      20872988..20873580
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080518.3 → NP_536779.2  turandot C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_536779.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IN43, Q962D9
      UniProtKB/TrEMBL
      A0A1B2AJ59
      Related
      FBpp0083379
      Conserved Domains (1) summary
      pfam07240
      Location:41 → 117
      Turandot; Stress-inducible humoral factor Turandot
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IN43.1 Q8IN43

    Gene LinkOut

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